DRSC/TRiP Functional Genomics Resources

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Protein Alignment sqa and trioa

DIOPT Version :9

Sequence 1:NP_001260832.1 Gene:sqa / 36002 FlyBaseID:FBgn0259678 Length:888 Species:Drosophila melanogaster
Sequence 2:XP_021323750.1 Gene:trioa / 557667 ZFINID:ZDB-GENE-060503-334 Length:3115 Species:Danio rerio


Alignment Length:287 Identity:101/287 - (35%)
Similarity:156/287 - (54%) Gaps:17/287 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 YDVLGEVGRGKFGTVYKCRDKANGLQLAAKFV--PIPKREDKRNVEREVEIMNSLQHHLIIQLYA 96
            |..:.|:|||:|..|.:|..:.:...:|.|||  .:.||:   .|..|..::..|||..:::|..
Zfish  2813 YTEVAELGRGRFSVVKRCDQRGSKRTVAVKFVNKKLMKRD---QVTHEFSVLQRLQHPHLVRLLD 2874

  Fly    97 AYEYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENI 161
            .:|......:|||:.:.|.|.|.:| ....|||.....::|.:.||:.::|...|||||||||| 
Zfish  2875 TFETSSSYALVLEMSDQGRLLDYIV-SWGNLTEEKVAFYLRDILEALQYLHNCRIVHLDLKPEN- 2937

  Fly   162 LVLTQKGNR--IKIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVNFDCISYGTDMWSVGVICYVL 224
            ||:.|..::  :|:.|||.|.:.:....:..|.|:|||.|||:|..|.:|..:|:||:||:.||:
Zfish  2938 LVVEQSPSQPLVKLTDFGDAVQLNSTPYVHPLLGSPEFAAPELVLGDPVSLSSDLWSLGVLTYVM 3002

  Fly   225 ISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWL 289
            :||.|||:.|:..||..|:....:.|.|:.|.|:|....||:..||..:.|.|..|..|::..||
Zfish  3003 LSGASPFLDESVEETCLNICRLDFSFPDDYFQGVSQAARDFMCLLLRMEPSKRPPATSCLQEPWL 3067

  Fly   290 QQRPATAATATPITKAASAASKSRLKS 316
            :        |....::|.....|||.|
Zfish  3068 R--------AGGGRRSAECIDTSRLIS 3086

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sqaNP_001260832.1 S_TKc 34..289 CDD:214567 93/258 (36%)
STKc_MLCK 40..289 CDD:271005 91/252 (36%)
trioaXP_021323750.1 SEC14 61..199 CDD:214706
SPEC 212..447 CDD:238103
SPEC 343..589 CDD:238103
SPEC 590..806 CDD:238103
SPEC 810..1037 CDD:238103
SPEC 931..1160 CDD:238103
SPEC 1166..1266 CDD:197544
RhoGEF 1316..1488 CDD:238091
PH1_Kalirin_Trio_like 1495..1627 CDD:270060
SH3_Kalirin_1 1695..1754 CDD:212786
SH3-RhoG_link 1752..2000 CDD:318750
RhoGEF 2007..2180 CDD:238091
PH2_Kalirin_Trio_p63RhoGEF 2185..2324 CDD:270061
Atrophin-1 <2364..2523 CDD:331285
SH3_Kalirin_2 2570..2628 CDD:212787
I-set 2702..2793 CDD:254352
PKc_like 2805..3067 CDD:328722 93/258 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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