DRSC/TRiP Functional Genomics Resources

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Protein Alignment sqa and Strn-Mlck

DIOPT Version :10

Sequence 1:NP_724821.2 Gene:sqa / 36002 FlyBaseID:FBgn0259678 Length:888 Species:Drosophila melanogaster
Sequence 2:NP_001261019.1 Gene:Strn-Mlck / 36753 FlyBaseID:FBgn0265045 Length:8255 Species:Drosophila melanogaster


Alignment Length:816 Identity:234/816 - (28%)
Similarity:365/816 - (44%) Gaps:208/816 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 FPMRDVTINRNVDAHKHYDVLGEVGRGKFGTVYKCRDKANGLQ-LAAKFVPIPKREDKRNVEREV 80
            |....|::....|....::::.|:|:|:||.|||.:::....| ||||.:...|.:|::.|..|:
  Fly  7603 FGQATVSVQSGGDFKSRFEIIEELGKGRFGIVYKVQERGQPEQLLAAKVIKCIKSQDRQKVLEEI 7667

  Fly    81 EIMNSLQHHLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAF 145
            .||.:|||..::||.|::|..:.:.:|:|.|.|||||:|||.|:|.|||..|.:|:||||:.:|:
  Fly  7668 SIMRALQHPKLLQLAASFESPREIVMVMEYITGGELFERVVADDFTLTEMDCILFLRQVCDGVAY 7732

  Fly   146 IHGNGIVHLDLKPENILVLTQKGNRIKIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVNFDCISY 210
            :||..:||||||||||:..|:..::|||||||||::.|....:|||||||||:.||:::::.|.:
  Fly  7733 MHGQSVVHLDLKPENIMCHTRTSHQIKIIDFGLAQRLDTKAPVRVLFGTPEFIPPEIISYEPIGF 7797

  Fly   211 GTDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLS 275
            .:||||||||||||:||||||||:.|:||.||:|.|.||::||.|:.:|.|..|||::||.....
  Fly  7798 QSDMWSVGVICYVLLSGLSPFMGDTDVETFSNITRADYDYDDEAFDCVSQEAKDFISQLLVHRKE 7862

  Fly   276 TRMTAAECMKHKWLQQRPATAATATPITKAASAASKSRLKSVSPVTAPSESSEDSTETIEDEDDE 340
            .|:||.:|:..|||.|||                                               
  Fly  7863 DRLTAQQCLASKWLSQRP----------------------------------------------- 7880

  Fly   341 EEVAVQQAKQKDQQQDEELANLCGDAELENKELDATKDNLKNFIVR--WETHPNSPYVFDVEGNV 403
                           |:.|:|        ||   ...|.||.||:|  |:.          .||.
  Fly  7881 ---------------DDSLSN--------NK---ICTDKLKKFIIRRKWQK----------TGNA 7909

  Fly   404 IAPLSE-----------------TSYPHPRRTHGADSLSSSRVCS--PSPCDSISTLTDDERGDI 449
            |..|..                 .|.|.| ...|...|::|.:.|  .|...|:....||..|::
  Fly  7910 IRALGRMANLSVSRRNSAIAMGVLSSPRP-SISGLGMLTTSAIGSGTSSQMTSLHEEEDDFSGEM 7973

  Fly   450 EDLPE------EDESRSAE-NESPRSVATPINESREKLFPTVATS-------SPSTPTPQHLFNE 500
            ..:.:      .|:|:.:| ::|..|..:..:.::|.|..::|.|       :.:.||..|    
  Fly  7974 PPVEKRTVLKLRDKSQCSERSDSGYSECSNCSGAQETLLLSLAKSKLEAIAKASTLPTVVH---- 8034

  Fly   501 NFDEFSGSQSTAQQQRSMKS-YLHTFDRRNSDTTYLLGRRSSGERVNLADEIRKLSDHLLMLAEI 564
            :.::....:...:.:..|:| :.:|...|...    |...::.|:.....:::.|      |.|.
  Fly  8035 DTEQPVSLELPTKGEAIMRSDFTNTIKMRKKS----LEDSAAREKPRSKPQVKPL------LCES 8089

  Fly   565 NTKLGDANNNGSSSGAPADPPAAAAAAAAPVPTSTAPASVAPSGSTS--SKTSEISQEGNRWTSK 627
            ..|:....:....|.|||...|:|:||..| |.:..|..:|...|..  |:|.|..:.|.     
  Fly  8090 KLKVSQLKDRFQVSPAPASASASASAANKP-PLAYGPFKIAKVASVGRISRTEEPGRSGR----- 8148

  Fly   628 TTSSSSWNRPTLKGGLFSQASSSSQSQSTYDDGKGKTKISSLSVRLQQSIEETPKLSNGNSSSSK 692
                   ..|::                   .||||    |..||   |:..:|           
  Fly  8149 -------GAPSV-------------------SGKGK----SPQVR---SMPSSP----------- 8169

  Fly   693 SLVQSQRKSTVQTMSSSNARSFTNQQVQRTSTTSSKVISSSTRSSNTSSSNYIASNASNSISTSA 757
               ..||.:|...:.|...|....:..|:.:..|::....:.|.:.|.:.|              
  Fly  8170 ---LPQRSATPTRLMSQRVREAAERLAQQHTVASAQRHLGNGRGTGTGNGN-------------- 8217

  Fly   758 SNPSSTGASNPITTSASNESASSRRAKFRINQMSRD 793
            .|.:|.|..|..|...:.||    ||:..||:.:.:
  Fly  8218 GNSNSNGNGNGNTAETNRES----RARRLINRFNSE 8249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sqaNP_724821.2 STKc_MLCK 40..289 CDD:271005 127/249 (51%)
Strn-MlckNP_001261019.1 Ig_3 26..112 CDD:464046
Ig <70..112 CDD:472250
Ig strand E 92..96 CDD:409353
Ig strand F 106..111 CDD:409353
Ig 137..226 CDD:472250
Ig strand B 154..158 CDD:409353
Ig strand C 167..171 CDD:409353
Ig strand E 192..196 CDD:409353
Ig strand F 206..211 CDD:409353
Ig strand G 219..222 CDD:409353
Ig 235..314 CDD:472250
Ig strand B 251..255 CDD:409564
Ig strand C 264..268 CDD:409564
Ig strand E 280..284 CDD:409564
Ig strand F 294..299 CDD:409564
Ig strand G 307..310 CDD:409564
Ig_3 336..414 CDD:464046
Ig 438..513 CDD:472250
Ig strand B 454..458 CDD:409564
Ig strand C 467..471 CDD:409564
Ig strand E 483..487 CDD:409564
Ig strand F 493..498 CDD:409564
Ig strand G 506..509 CDD:409564
Ig 537..628 CDD:472250
Ig strand B 554..558 CDD:409353
Ig strand C 567..571 CDD:409353
Ig strand F 607..612 CDD:409353
Ig strand G 620..623 CDD:409353
Ig 636..713 CDD:472250
Ig strand B 652..656 CDD:409564
Ig strand C 665..669 CDD:409564
Ig strand E 681..685 CDD:409564
Ig strand F 695..700 CDD:409564
Ig strand G 708..711 CDD:409564
SMC_N <2131..2664 CDD:481474
PTZ00121 <2600..3256 CDD:173412
PTZ00121 <3635..4609 CDD:173412
PTZ00121 <4215..5072 CDD:173412
I-set 5300..5388 CDD:400151
Ig strand B 5317..5321 CDD:409353
Ig strand C 5329..5333 CDD:409353
Ig strand E 5354..5358 CDD:409353
Ig strand F 5368..5373 CDD:409353
Ig_3 5399..5477 CDD:464046
Ig 5542..5627 CDD:472250
Ig strand B 5556..5560 CDD:409353
Ig strand C 5568..5572 CDD:409353
Ig strand E 5593..5597 CDD:409353
Ig strand F 5607..5612 CDD:409353
Ig 5654..5721 CDD:409353
Ig strand B 5654..5658 CDD:409353
Ig strand C 5665..5669 CDD:409353
Ig strand E 5690..5694 CDD:409353
Ig strand F 5704..5709 CDD:409353
Ig strand G 5718..5721 CDD:409353
I-set 5784..5874 CDD:400151
Ig strand B 5801..5805 CDD:409353
Ig strand C 5814..5818 CDD:409353
Ig strand E 5840..5844 CDD:409353
Ig strand F 5854..5859 CDD:409353
Ig 5902..5963 CDD:409353
Ig strand B 5902..5906 CDD:409353
Ig strand C 5915..5919 CDD:409353
Ig strand E 5941..5945 CDD:409353
Ig strand F 5955..5960 CDD:409353
Ig 5997..6086 CDD:472250
Ig strand B 6014..6018 CDD:409353
Ig strand C 6028..6032 CDD:409353
Ig strand E 6050..6056 CDD:409353
Ig strand F 6066..6071 CDD:409353
Ig strand G 6079..6082 CDD:409353
Ig 6107..6187 CDD:472250
Ig strand B 6115..6119 CDD:409353
Ig strand C 6128..6132 CDD:409353
Ig strand E 6153..6157 CDD:409353
Ig strand F 6167..6172 CDD:409353
Ig strand G 6180..6183 CDD:409353
FN3 6216..6310 CDD:238020
I-set 6321..6412 CDD:400151
Ig strand B 6339..6343 CDD:409353
Ig strand C 6352..6356 CDD:409353
Ig strand E 6375..6382 CDD:409353
Ig strand F 6392..6397 CDD:409353
Ig strand G 6405..6408 CDD:409353
I-set 6442..6531 CDD:400151
Ig strand B 6459..6463 CDD:409353
Ig strand C 6472..6476 CDD:409353
Ig strand E 6497..6501 CDD:409353
Ig strand F 6511..6516 CDD:409353
Ig strand G 6524..6527 CDD:409353
Ig 6541..6632 CDD:472250
Ig strand B 6559..6563 CDD:409353
Ig strand C 6572..6576 CDD:409353
Ig strand E 6598..6602 CDD:409353
Ig strand F 6612..6617 CDD:409353
Ig strand G 6625..6628 CDD:409353
Ig 6662..6754 CDD:472250
Ig strand B 6679..6683 CDD:409353
Ig strand C 6692..6696 CDD:409353
Ig strand E 6720..6724 CDD:409353
Ig strand F 6734..6739 CDD:409353
I-set 6779..6868 CDD:400151
Ig strand B 6796..6800 CDD:409353
Ig strand C 6809..6813 CDD:409353
Ig strand E 6834..6838 CDD:409353
Ig strand F 6848..6853 CDD:409353
I-set 6939..7028 CDD:400151
Ig strand B 6956..6960 CDD:409353
Ig strand C 6969..6973 CDD:409353
Ig strand E 6993..6998 CDD:409353
Ig strand F 7008..7013 CDD:409353
Ig strand G 7021..7024 CDD:409353
IG_like 7075..7140 CDD:214653
Ig strand C 7082..7086 CDD:409353
Ig strand E 7107..7111 CDD:409353
Ig strand F 7121..7126 CDD:409353
Ig strand G 7135..7138 CDD:409353
Ig 7173..7232 CDD:409353
Ig strand C 7184..7188 CDD:409353
Ig strand E 7210..7214 CDD:409353
Ig strand F 7224..7229 CDD:409353
IG_like 7406..7475 CDD:214653
Ig strand B 7413..7417 CDD:409353
Ig strand C 7426..7430 CDD:409353
Ig strand E 7451..7455 CDD:409353
Ig strand F 7465..7470 CDD:409353
FN3 7489..7588 CDD:238020
STKc_MLCK 7626..7876 CDD:271005 127/249 (51%)
Blue background indicates that the domain is not in the aligned region.

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