DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqa and mek1

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_594908.1	Gene:	mek1 / 2541604	PomBaseID:	SPAC14C4.03	Length:	445	Species:	Schizosaccharomyces pombe

Alignment Length:	305	Identity:	92/305 - (30%)
Similarity:	139/305 - (45%)	Gaps:	33/305 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 HYDVLGE--------VGRGKFGTVYKCRDKANGLQLAAKFVPIPKREDKRNVE-REVEIMNSLQH 88
            |::..||        :|.|.|..:|...|...|.|.|.|.:...|...||..| .|:.|:..|.|
pombe   151 HHEYAGERFNITQRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKLDH 215

  Fly    89 HLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIR-QVCEAMAFIHGNGIV 152
            ..||::...|..:....:..|::.||:||..:.  :......|..:||. |:.:.:.::|...|:
pombe   216 PNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLT--KLGTVPEVTTLFIMFQILQGLKYLHEQNII 278

  Fly   153 HLDLKPENILVLTQKGN--RIKIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVNF---------D 206
            |.|||.||||:.:....  ||.:.|||:||.....|||....||||:.|||:...         :
pombe   279 HRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVEKEN 343

  Fly   207 CISYG--TDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKL 269
            ...||  .|:||:|||.::|:||.||...:       .|...:.||.|..:..:|.:..|.|:.|
pombe   344 SSGYGKEVDLWSLGVIMFLLLSGNSPSFAD-------GVKEKQVDFRDPVWKSVSRQAKDLISNL 401

  Fly   270 LAKDLSTRMTAAECMKHKWLQQRPATAATATPITKAASAASKSRL 314
            |..:...|.|..:|:.|.|. .|.::..|....|:.......|||
pombe   402 LKTNPPDRFTVKQCLSHPWF-ARHSSRLTKLYETRILKPLKHSRL 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	84/277 (30%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	82/263 (31%)
mek1	NP_594908.1	FHA	39..141	CDD:238017
		STKc_CAMK	163..420	CDD:270687	82/265 (31%)
		S_TKc	164..421	CDD:214567	82/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930