DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqa and Pskh1

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_775608.1	Gene:	Pskh1 / 244631	MGIID:	3528383	Length:	424	Species:	Mus musculus

Alignment Length:	338	Identity:	110/338 - (32%)
Similarity:	171/338 - (50%)	Gaps:	30/338 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 YDVLGEVGRGKFGTVYKCRDKANGLQLAAKFVPIPKREDKRNVEREVEIMNSLQHHLIIQLYAAY 98
            ||:...:|||.|..|.:...:|.....|.|.:....||.:...|.|:.::..::|..||||...:
Mouse    98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVF 162

  Fly    99 EYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILV 163
            |.|:.:.:|:||..|||||||:: .:...|||.....::.|.:.:.::|..||.|.||||||:|.
Mouse   163 ETQERVYMVMELATGGELFDRII-AKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLY 226

  Fly   164 LTQKGNRIKII--DFGL--ARKFDPDKRLRVLFGTPEFVAPEVVNFDCISYGTDMWSVGVICYVL 224
            . ..|...|||  ||||  |||...|..::...||||::||||:.....:...|||::|||.|:|
Mouse   227 Y-HPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYIL 290

  Fly   225 ISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWL 289
            :||..||..:|.......:...||.:..|.:..:|....|||.:||..|...||||.:.::|.|:
Mouse   291 LSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355

  Fly   290 QQRPATAATATPITKAASAASKSRLKSVS-----------PVTAPSESSEDSTETIEDEDDE-EE 342
                        ::.|||::.|:..:|:|           ..|..|:|:..|..|..::... .|
Mouse   356 ------------VSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRE 408

  Fly   343 VAVQQAKQKDQQQ 355
            ..:::...:.|||
Mouse   409 RELRELNLRYQQQ 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	94/258 (36%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	92/252 (37%)
Pskh1	NP_775608.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..79
		STKc_PSKH1	96..355	CDD:270989	94/258 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..408		5/29 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900