DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqa and Phkg1

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_035209.1	Gene:	Phkg1 / 18682	MGIID:	97579	Length:	388	Species:	Mus musculus

Alignment Length:	344	Identity:	98/344 - (28%)
Similarity:	154/344 - (44%)	Gaps:	45/344 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DDSEPEGVLEPAFPMRDVTINRNVDAHKHYDVLGEVGRGKFGTVYKCRDKANGLQLAAKFVPI-- 67
            ||:.|:......|             :::|:....:|||....|.:|..|....:.|.|.:.|
Mouse     4 DDALPDSHSAQTF-------------YENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITG 55

  Fly    68 -------PKREDKRNVEREVEIMNSLQ-HHLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDE 124
                   ..:|.:....:||:|:..:. |..||||...||......:|.:|::.||||| .:.::
Mouse    56 GGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFD-YLTEK 119

  Fly   125 FVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQKGNRIKIIDFGLARKFDPDKRLR 189
            ..|||:..|..:|.:.|.:..:|...|||.||||||||:  .....||:.|||.:.:..|.::||
Mouse   120 VTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILL--DDNMNIKLTDFGFSCQLQPGEKLR 182

  Fly   190 VLFGTPEFVAPEVVNFDCI------SYG--TDMWSVGVICYVLISGLSPFMGENDIETMSNVTIA 246
            .:.|||.::|||::  .|.      .||  .||||.|||.|.|::|..||.....:..:..:...
Mouse   183 EVCGTPSYLAPEII--QCSMDDGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDG 245

  Fly   247 KYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWLQQ---------RPATAATATPI 302
            ||.|....::..|....|.:::.|......|.:|.|.:.|.:.|:         .|........:
Mouse   246 KYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFFQEYVVEEVRHFSPRGKFKVICL 310

  Fly   303 TKAASAASKSRLKSVSPVT 321
            |..||.....:.:.|.|||
Mouse   311 TVLASVKIYYQYRRVKPVT 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	85/272 (31%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	84/266 (32%)
Phkg1	NP_035209.1	PKc_like	16..291	CDD:328722	87/292 (30%)
		Calmodulin-binding (domain-N)	303..327		4/23 (17%)
		Calmodulin-binding (domain-C)	343..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030