Protein Alignment sqa and mlck-1

DIOPT Version :9

• Sequence 1: NP_001260832.1
• Gene: sqa / 36002
• FlyBaseID: FBgn0259678
• Length: 888
• Species: Drosophila melanogaster
• Sequence 2: NP_509689.1
• Gene: mlck-1 / 181217
• WormBaseID: WBGene00013869
• Length: 1211
• Species: Caenorhabditis elegans
• Alignment Length: 1095
• Identity: 269/1095 - (24%)
• Similarity: 443/1095 - (40%)
• Gaps: 282/1095 - (25%)

  Fly     2 IYIDDSEPEGVLEPAFPMRDVTINRNVDAHKHYDVLGEV----GRGKFGTVYKCRDKANGLQLAA 62
            |.:|:..|..:.||  |:.||....|:.|:..:|.|.:|    |.||||.||...:|..|.:.||
 Worm    11 IKVDEHYPSELDEP--PVFDVKKIENIRANVKFDTLYQVTKLLGDGKFGKVYCVIEKETGKEFAA 73

  Fly    63 KFVPIPKREDKRNVEREVEIMNSLQHHLIIQLY-AAYEYQKMMCVVLELIEGGELFDRVVDDEFV 126
            ||:.|.|..|:..|||||.|:..|:|..|.|:| |.|.....:.:::|::.||||||||.::.:|
 Worm    74 KFIKIRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYV 138

  Fly   127 LTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQKGNRIKIIDFGLARKFDPDKRLRVL 191
            |:|....:.|.|:|||:.:||...|:|||:|||||:.::..|||||:|||||||.:|..:.|:.:
 Worm   139 LSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSLTGNRIKLIDFGLARHYDGTQELKYM 203

  Fly   192 FGTPEFVAPEVVNFDCISYGTDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECFN 256
            .|||||.||||:.|:.:.|.|||||:|||.|:|:||.|||:|:|..||..||....::|.:| |:
 Worm   204 AGTPEFAAPEVIKFEKLDYHTDMWSIGVITYILLSGYSPFLGDNLGETYCNVEKGVWEFTEE-FD 267

  Fly   257 GISPECLDFIAKLLAKDLSTRMTAAECMKHKWLQQRPATAATATPITKAASAAS----------- 310
            .::.|..||:.|||..|.|.||...||::|.|:.:....||..|.:.|..:|.:
 Worm   268 TVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWIAKHRQKAACNTILEKPLNAPTLDNKQIMRYNA 332

  Fly   311 ------------------------KSRL-----KSVSPVTAPSESSEDSTE-------------- 332
                                    |:|:     |...|:...:|..|....
 Worm   333 RRKFRRMIIYVKFLIEMNRLRNSLKTRMSANGHKFFDPLLKMAEKKEQKISNAIGTAGCPASGLG 397

  Fly   333 -----TIEDEDDEEEVAVQQ-------AKQKDQQQDEELANLCGDAELE------NKELDATKDN 379
                 .::.:....:|.|.|       .:::::::.:::||..|..:.|      .|:|..|..:
 Worm   398 SLVKMAVDSQKKNGDVPVTQDANMSTEPEKEEKKKKKKIANADGSTKTEKTSSVKKKKLVETDGD 462

  Fly   380 ---------------------------LKNFIVRWETHPNSPYVFDVEGNVIAPLSETSYPHPRR 417
                                       |||..|  ..:.|||    ...::.:...|...|..::
 Worm   463 AGLRPPPELMTKRASTGGESLLAAVKVLKNLEV--VENGNSP----KRKSLCSVKEEKEIPAKKQ 521

  Fly   418 THGADSLSSSRVCSPSPCDSISTLTDDERGDI--EDLPEEDESRSAENES---PRSVAT-PINES 476
            |.|                 ..||...|.|||  :..|.:.::.:.::.|   |:.:.| |..|.
 Worm   522 TEG-----------------YKTLETTENGDIRRKSAPVKQDTLTCQDNSKVTPQLLETAPNGEI 569

  Fly   477 REKLFPTVATSSPSTPTPQHLFNE-------------------------NFDEFSGSQSTAQQQR 516
            |.|   :.:.....:..|:.:..:                         :.|| .|.:...::::
 Worm   570 RRK---SASAKEEKSVKPEEVIRKKSSASVKETKTVELSVVPVKLEKLASIDE-KGEKLVKKKKK 630

  Fly   517 SM---------KSYLHTFDRRNSDTTYLLG----------RRSSGERVNLADEIRKLSDHLLMLA 562
            :.         ||.:.:.:.:..:...||.          |||.|.:  .|.|.:.:....|.:.
 Worm   631 TTTVTAEIEKPKSVIESKEEKLVEKPKLLNGTLVSDALEKRRSLGSK--RASETQDVGLRPLPVV 693

  Fly   563 EINTK--LGDANNNGSSSGAPADPPAAAAAAAAPVPTSTAPASVAPSGSTSSKTSEISQEGNRWT 625
            :.:.|  |.|......|...||:|      ....||.:..||.   .|:...:...:....|...
 Worm   694 DFSPKIVLTDKKEPKESKTKPAEP------LKEIVPETKKPAR---QGALRKRDKSLDDILNAAP 749

  Fly   626 SKTTSSSSWNRPTLKGGLFSQASSSSQ---SQSTYDDGKGKTKISSLSVRLQQSIEE----TPKL 683
            |.||.|.| ...::|..:......|.:   |:......|...|..|:..||...|.|    .|||
 Worm   750 SPTTLSKS-TVTSVKHSVVETIHPSGEIIKSEKVLTKKKSLKKDKSIDDRLPVKIIEDKASLPKL 813

  Fly   684 --------SNGNSSSSK---------SLVQSQRKSTVQTMSSSNARSFTNQ---QVQRTSTTSSK 728
                    |.....:||         :|::.::|.|...|:|....:.|.|   .|:||:.:|.|
 Worm   814 KTDVVTFESKPVKKTSKIVKLIPEDANLIKDEKKPTKIVMTSEKQATTTVQTTTSVKRTTKSSEK 878

  Fly   729 VIS--------SSTRSSNTSSSNYIASNASNSISTSASNPSS--TGASNPI------TTSASNES 777
            .:.        .|::..|:...:...|..:......::.|:.  |...|.:      :||.....
 Worm   879 KVEHTADGKSVESSQKKNSQKDDVKVSQVTTKKEEDSTQPAPTLTVKKNVVKQTAEKSTSEKEHK 943

  Fly   778 ASSRRAKFRINQMS---RDVPVGLPDTHQTVNLEEAANTTKDCLLHLLEKYNETRIRNPVGRHQS 839
            .:..:.:.||.:.|   :|..|......|::.:..             ||:.|:::   :|..
 Worm   944 TTENKEQERIIKKSSTLKDKDVAQVSLQQSIKVNG-------------EKHKESKV---IGTK-- 990

  Fly   840 ISVDWRVSDNLEYRSMSSINAFFQRHNPNGG----------GHNVRHIQAQLEEK 884
                 .|.:.||.:...:|||     ||...          |...:|::...:.|
 Worm   991 -----TVINKLELKGEETINA-----NPKKSSLKKATAKVTGETTKHLEISTDGK 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	122/259 (47%)
		STKc_MLCK	40..289	CDD:271005	120/253 (47%)
mlck-1	NP_509689.1	PKc_like	51..300	CDD:389743	119/249 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000818
OrthoInspector	1	1.000	-	-		oto19694
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24347
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940