DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqa and zyg-8

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_499571.2	Gene:	zyg-8 / 176639	WormBaseID:	WBGene00006993	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	78/264 - (29%)
Similarity:	126/264 - (47%)	Gaps:	22/264 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VGRGKFGTVYKCRDKANGLQLAAKFVPIPKRED----KRNVEREVEIMNSLQHHLIIQLYAAYEY 100
            :|.|....||:..||.|...  .|.:.:..||:    :..:|.|:.|:..:.|..|:|||..:..
Worm   488 IGDGNTAVVYEVIDKTNNDD--RKAMKVIARENVIGKEHLIEMELAILQKIDHTFIVQLYDHWFV 550

  Fly   101 QKMMCVVLELIEGGELFD-----RVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPEN 160
            .....:.|||||.|:||:     |.|.:...:....|      :.:|:.:||..||||.|:|.||
Worm   551 DDSYYLSLELIEMGDLFEHLRIVRRVPERDAVRMMTC------LGQALEYIHELGIVHRDVKLEN 609

  Fly   161 ILVLTQKGNR--IKIIDFGLARKFDPD-KRLRVLFGTPEFVAPEVVNFDCISYGTDMWSVGVICY 222
            :|::..:...  :|:.|||||.:...| ..|..:.|||.:|||||:|........|:|:.|||.|
Worm   610 LLIVKDEFGELGVKLADFGLAAEMPKDFGVLSTICGTPTYVAPEVLNKTGYGCKVDIWAAGVILY 674

  Fly   223 VLISGLSPFMGENDIE--TMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMK 285
            .::.|..||...:..|  ..|.:...::.|....::.:|......|..|:..|...|.:|.|.:.
Worm   675 AILVGFPPFQSSDGSEQDLFSAIMSGEFSFPSPSWDDVSWSVRHLIMCLIHTDPFHRYSAGELLN 739

  Fly   286 HKWL 289
            .:|:
Worm   740 DEWM 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	77/262 (29%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	77/262 (29%)
zyg-8	NP_499571.2	DCX	206..298	CDD:214711
		DCX	335..423	CDD:214711
		STKc_DCKL	481..742	CDD:270997	77/261 (30%)
		S_TKc	482..743	CDD:214567	77/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900