DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqa and mylk3

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	XP_002931740.3	Gene:	mylk3 / 100498243	XenbaseID:	XB-GENE-980367	Length:	764	Species:	Xenopus tropicalis

Alignment Length:	321	Identity:	154/321 - (47%)
Similarity:	213/321 - (66%)	Gaps:	28/321 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IDDSEPEGVLEPA-FPMRDVTINR-------NVDAHKHYDVLGEVGRGKFGTVYKCRDKANGLQL 60
            |||..|    .|| |..|.|:|.:       :|..|   :|||  |||:||.|:||.:||.||||
Frog   427 IDDCPP----PPAPFNHRIVSIKQAILSSCYSVSQH---EVLG--GRGRFGQVHKCIEKATGLQL 482

  Fly    61 AAKFVPIPKREDKRNVEREVEIMNSLQHHLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDEF 125
            |||.:.:...:|:..|:.|:.:||.|.|..:||||.|:|.:..:.:::|.::|||||||:.|:.:
Frog   483 AAKIIKVKGAKDRDEVKNEINVMNQLNHVNLIQLYDAFECKNDLTLIMEYLDGGELFDRITDENY 547

  Fly   126 VLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQKGNRIKIIDFGLARKFDPDKRLRV 190
            .|||....:|.:|:||.:.::|...|:||||||||||.:.:.||:||||||||||::.|.::|:|
Frog   548 SLTELDAIMFTKQICEGIYYLHQQYILHLDLKPENILCVNRTGNQIKIIDFGLARRYKPREKLKV 612

  Fly   191 LFGTPEFVAPEVVNFDCISYGTDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECF 255
            .||||||:||||||:|.:|:.|||||||||.|:|:||||||:||:|.|||:.:....:|||.|.|
Frog   613 NFGTPEFLAPEVVNYDFVSFPTDMWSVGVITYMLLSGLSPFLGESDAETMNYIVNCNWDFESESF 677

  Fly   256 NGISPECLDFIAKLLAKDLSTRMTAAECMKHKWLQQRPATAATATPITKAASAASKSRLKS 316
            ..:|.|..|||:|||.|:.|.|::|.:|:||.||...|..|           ...|.||||
Frog   678 EQVSEEAKDFISKLLIKERSCRLSAGQCLKHDWLVNLPLKA-----------MKYKVRLKS 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	133/254 (52%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	130/248 (52%)
mylk3	XP_002931740.3	PKc_like	450..711	CDD:419665	135/265 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	289	1.000	Domainoid score	I1536
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000818
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2697
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000