Protein Alignment dap and Cdkn1b

DIOPT Version :10

• Sequence 1: NP_476948.1
• Gene: dap / 36001
• FlyBaseID: FBgn0010316
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_034005.2
• Gene: Cdkn1b / 12576
• MGIID: 104565
• Length: 197
• Species: Mus musculus
• Alignment Length: 235
• Identity: 57/235 - (24%)
• Similarity: 92/235 - (39%)
• Gaps: 61/235 - (25%)

  Fly     1 MVSARVLNPVMISEFCKMSSSPAVSRNLACGRQLNRIK----RDLFGSSKSAEGTANKTPFNSEL 61
            |.:.||.|           .||::.|..|  ||....|    |:||       |..|......:|
Mouse     1 MSNVRVSN-----------GSPSLERMDA--RQAEHPKPSACRNLF-------GPVNHEELTRDL 45

  Fly    62 ERH----QELATQKWGFDFRAGCPLAEKSPYIWERVSFQESSFAPEMYTLTRAAHVRP------- 115
            |:|    :|.:.:||.|||:...||  :..|.|:.|   |....||.|       .||
Mouse    46 EKHCRDMEEASQRKWNFDFQNHKPL--EGRYEWQEV---ERGSLPEFY-------YRPPRPPKSA 98

  Fly   116 -------SADASPSDMDI-LVNERSERENFGSNLVNSSLESNTDNESCYDSQDESLAMRLSSSST 172
                   |.|.|.|...: |:..::..|:  .:||: .:..::||.:....|...:..|.::..:
Mouse    99 CKVLAQESQDVSGSRQAVPLIGSQANSED--RHLVD-QMPDSSDNPAGLAEQCPGMRKRPAAEDS 160

  Fly   173 TSTSSIVLRKRQPKITEFMKERKRLAQAPKKLSPAKRMRT 212
            :|.:....|..: .:::.......:.|.|||  |..|.:|
Mouse   161 SSQNKRANRTEE-NVSDGSPNAGTVEQTPKK--PGLRRQT 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dap	NP_476948.1	CDI	41..91	CDD:460503	16/53 (30%)
Cdkn1b	NP_034005.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		14/52 (27%)
		CDI	32..77	CDD:460503	16/53 (30%)
		Interaction with CDK2. /evidence=ECO:0000250|UniProtKB:P46527	51..91		15/51 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..197		24/123 (20%)
		Nuclear localization signal. /evidence=ECO:0000255	153..169		2/15 (13%)