DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dap and CDKN1C

DIOPT Version :9

Sequence 1:	NP_476948.1	Gene:	dap / 36001	FlyBaseID:	FBgn0010316	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_000067.1	Gene:	CDKN1C / 1028	HGNCID:	1786	Length:	316	Species:	Homo sapiens

Alignment Length:	91	Identity:	24/91 - (26%)
Similarity:	31/91 - (34%)	Gaps:	22/91 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PAVSRNLACGRQLNRIKRDLFG----SSKSAEGTANKTPFNSELERHQELATQKWGFDFRAGCPL 82
            |.:.|..||        |.|||    ...|.|..|.....|:|.:       .:|.:||:...||
Human    22 PVLVRTSAC--------RSLFGPVDHEELSRELQARLAELNAEDQ-------NRWDYDFQQDMPL 71

  Fly    83 AEKSPYIWERVSFQESSFAPEMYTLT 108
            .......|..|   :|...|..|..|
Human    72 RGPGRLQWTEV---DSDSVPAFYRET 94

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dap	NP_476948.1	CDI	41..83	CDD:280409	12/45 (27%)
CDKN1C	NP_000067.1	CDI	32..78	CDD:308056	13/52 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..153
		9 X 4 AA repeats of P-A-P-A	156..213
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..260
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	278..316
		Nuclear localization signal. /evidence=ECO:0000255	278..281
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4743
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1595421at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10265
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920