Protein Alignment dap and CDKN1B

DIOPT Version :10

• Sequence 1: NP_476948.1
• Gene: dap / 36001
• FlyBaseID: FBgn0010316
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_004055.1
• Gene: CDKN1B / 1027
• HGNCID: 1785
• Length: 198
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 56/232 - (24%)
• Similarity: 91/232 - (39%)
• Gaps: 57/232 - (24%)

  Fly     1 MVSARVLNPVMISEFCKMSSSPAVSRNLACGRQLNRIK----RDLFGSSKSAEGTANKTPFNSEL 61
            |.:.||.|           .||::.|..|  ||....|    |:|||.....|.|       .:|
Human     1 MSNVRVSN-----------GSPSLERMDA--RQAEHPKPSACRNLFGPVDHEELT-------RDL 45

  Fly    62 ERH----QELATQKWGFDFRAGCPLAEKSPYIWERVSFQESSFAPEMY-------------TLTR 109
            |:|    :|.:.:||.|||:...||..|  |.|:.|   |....||.|             ....
Human    46 EKHCRDMEEASQRKWNFDFQNHKPLEGK--YEWQEV---EKGSLPEFYYRPPRPPKGACKVPAQE 105

  Fly   110 AAHVRPSADASPSDMDILVNERSERENFGSNLVNSSLESNTDNESCYDSQDESLAMRLSSSSTTS 174
            :..|..|..|:|     |:...:..|:  ::||:...:. :|:::....|...:..| .::..:|
Human   106 SQDVSGSRPAAP-----LIGAPANSED--THLVDPKTDP-SDSQTGLAEQCAGIRKR-PATDDSS 161

  Fly   175 TSSIVLRKRQPKITEFMKERKRLAQAPKKLSPAKRMR 211
            |.:....:.:..:::.......:.|.|||  |..|.|
Human   162 TQNKRANRTEENVSDGSPNAGSVEQTPKK--PGLRRR 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dap	NP_476948.1	CDI	41..91	CDD:460503	18/53 (34%)
CDKN1B	NP_004055.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		13/45 (29%)
		CDI	32..77	CDD:460503	18/53 (34%)
		Interaction with CDK2. /evidence=ECO:0000269|PubMed:28666995	51..91		16/44 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..198		23/123 (19%)
		Nuclear localization signal. /evidence=ECO:0000255	153..169		3/16 (19%)