Protein Alignment CG10459 and STRAP

DIOPT Version :10

• Sequence 1: NP_610513.2
• Gene: CG10459 / 36000
• FlyBaseID: FBgn0033440
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_009109.3
• Gene: STRAP / 11171
• HGNCID: 30796
• Length: 350
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 119/322 - (36%)
• Similarity: 164/322 - (50%)
• Gaps: 31/322 - (9%)

  Fly     9 CPGHSDSVVELSFNRDYDTGYFLASAGLDGVAALRHGDTGDCITHLRKHTDSVWSVSLSHDAKIL 73
            |.||:..||:|:|:.....||||.||..||...||.|||||.|.....|..:||..:|:.||...
Human    10 CSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKA 74

  Fly    74 ASGGADCKVRVWDALLGKQLKKLRHTKTVACVDLNPKATRLLTGCIDQESPLALFDMEQSEKAPL 138
            |:..||...:||||:.|.:|..|.|...|..||....:..||||  .|:..|.::|:.:.|..|
Human    75 ATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTG--GQDKLLRIYDLNKPEAEP- 136

  Fly   139 MEFRGHSRGVRDVIFCLEEHCFLSSSYDRTVRMWDCRTGTRTNSIFLPHHVKSLELHHSGDIVTI 203
            .|..||:.|::..::|.|:...||:. |:|||:||..|.|...|:.....|.|:|....|:|:.|
Human   137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVI 200

  Fly   204 AYAGGVIF-----LDP-KSFEVLKHRKLPYKVTAASLSPNKGIYVCGNNMGYSFKYDYDTDVDRG 262
            .|...:.|     ||| ||||.      |..:.:|||.|.|...|.|......:||||::..:..
Human   201 TYGRSIAFHSAVSLDPIKSFEA------PATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELE 259

  Fly   263 LYVSQEPSAVLALSFSPDGEVCAIGSQDGSIILWQMNPKQASVVGH--------LKDEDDGE 316
            .|.... ..:..:.||||||:.|.||:||::.|||      :|||.        |.:||.||
Human   260 SYKGHF-GPIHCVRFSPDGELYASGSEDGTLRLWQ------TVVGKTYGLWKCVLPEEDSGE 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10459	NP_610513.2	WD40	<11..299	CDD:441893	110/293 (38%)
		WD40 repeat	61..97	CDD:293791	14/35 (40%)
		WD40 repeat	103..143	CDD:293791	12/39 (31%)
		WD40 repeat	148..185	CDD:293791	13/36 (36%)
		WD40 repeat	190..222	CDD:293791	14/37 (38%)
		WD40 repeat	229..264	CDD:293791	11/34 (32%)
		WD40 repeat	272..298	CDD:293791	13/25 (52%)
STRAP	NP_009109.3	WD40	<4..294	CDD:441893	111/300 (37%)
		WD 1	12..56		22/43 (51%)
		WD 2	57..96		15/38 (39%)
		WD 3	98..137		13/41 (32%)
		WD40 repeat	104..141	CDD:293791	12/39 (31%)
		WD 4	141..179		15/38 (39%)
		WD40 repeat	146..181	CDD:293791	13/35 (37%)
		WD 5	180..212		8/31 (26%)
		WD40 repeat	187..221	CDD:293791	12/33 (36%)
		WD 6	221..262		13/46 (28%)
		WD40 repeat	226..262	CDD:293791	11/35 (31%)
		WD 7	263..302		17/45 (38%)