Protein Alignment AQP3 and Eglp4

DIOPT Version :10

• Sequence 1: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_001261154.1
• Gene: Eglp4 / 37739
• FlyBaseID: FBgn0034885
• Length: 297
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 86/273 - (31%)
• Similarity: 123/273 - (45%)
• Gaps: 50/273 - (18%)

Human    26 LAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAM 90
            |.|.:||.|||..||....:..|....|   |.|.|.|||||.:.|...|.|||||||||||.|
  Fly    61 LGELIGTGILVFLGCMGCVKTDLFPNNH---LQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVA- 121

Human    91 CFLAREPWIKLPI-YTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGT----AGIFATY 150
            .::.....:::.. |..||.||||:|.|:                |.|..|:.|    ||:..|.
  Fly   122 AYIYEMVTLRMAFAYFAAQMLGAFIGYGL----------------LMVLLPSPTLTVGAGLCVTL 170

Human   151 PSGHLDMINGFFDQFIGTASLIVCVLAIV-----DPYNNPVPRGLEAFTVGLVVLVIGTSMGFNS 210
            |  |..:..|   |.:|...:|..:|.||     ||.|:.....: ....||.:..:..:.|..:
  Fly   171 P--HTSVTTG---QALGIEFVITSILVIVCCGVWDPRNSKFHDSV-GIRFGLAIACLACAAGPFT 229

Human   211 GYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPS 275
            |.::||||.|.|.|      |... |.:...:|..|:.|..:.:.|...|::..:   :|....|
  Fly   230 GGSMNPARSFAPAL------WNKH-FESNWIYWLAPLSSSAITAYAYKVVFRREV---VEAEITS 284

Human   276 NEE----ENVKLA 284
            ||:    |:|:|:
  Fly   285 NEKLRQLEDVQLS 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP3	NP_004916.1	MIP	23..264	CDD:238204	79/247 (32%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:O14520	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:O14520	215..217		1/1 (100%)
Eglp4	NP_001261154.1	MIP	59..272	CDD:444743	78/243 (32%)