Protein Alignment AQP3 and Eglp3

DIOPT Version :10

• Sequence 1: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_611812.2
• Gene: Eglp3 / 37738
• FlyBaseID: FBgn0034884
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 79/301 - (26%)
• Similarity: 128/301 - (42%)
• Gaps: 55/301 - (18%)

Human     1 MGRQKELVSRCGEMLHIRYRL---LRQALA----ECLGTLILVMFGCGSVAQVVLSRGTHGGFLT 58
            |.:||:.......  :.|:||   .|.|:|    |...|.:.|...|....:..|.:.:|   ..
  Fly     1 MSQQKQKSQESNP--NARWRLEGHQRSAIACFFGELAATAVFVFIACMGCVETPLFQNSH---FR 60

Human    59 INLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLY 123
            ..|.||.|:.:.|...|.|||||||||:|.|........||:...|.:||..||.:|.|::..:
  Fly    61 SGLTFGLAILIAIQCFGSVSGAHLNPAITLAAWLYGAIGWIRAIAYFVAQAAGALIGYGLLVAV- 124

Human   124 YDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNN---- 184
                  ...|.  :.|.:..:|:..|..:..:.::.|.|.:|:.|..|::...::.||.|.
  Fly   125 ------LPGNS--IKGVDNPSGVCVTILAPGISVLQGVFIEFLITCCLVMVACSVWDPRNAKLQD 181

Human   185 --PVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHW-WWVP 246
              ||..||   ||..::|    :.|..:|.::||.|..||      |.|..   :...|| :|
  Fly   182 SVPVRFGL---TVSCLIL----TAGLFTGASMNPTRSLGP------AVWND---SWAHHWIYW-- 228

Human   247 IVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVK 287
             |.||:.......:|::..        ..:||.:::.:..|
  Fly   229 -VGPLVAGAVTSLIYRMAF--------KGDEEIDLRTSDAK 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP3	NP_004916.1	MIP	23..264	CDD:238204	70/251 (28%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:O14520	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:O14520	215..217		1/1 (100%)
Eglp3	NP_611812.2	MIP	30..244	CDD:444743	67/244 (27%)