Protein Alignment AQP3 and Prip

DIOPT Version :10

• Sequence 1: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 85/295 - (28%)
• Similarity: 120/295 - (40%)
• Gaps: 62/295 - (21%)

Human     3 RQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAV 67
            :.|||            ||.:..:.|.||.|||..|.||:..|:     ..|.|..  ||||.|:
  Fly    14 KSKEL------------RLWQALIGEFLGNLILNFFACGACTQI-----EDGTFKA--LAFGLAI 59

Human    68 TLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGL----YYDAIW 128
            .:.|.|.|.:||.|:|||||..|....|...|:...|.:.|.|||..|...|..|    ||:.:.
  Fly    60 FMAITIVGHLSGGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLG 124

Human   129 HFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAF 193
            |.:      ..||.|.             :.|...:|.....|::.|....||: .|..|.....
  Fly   125 HTS------LAPNITE-------------LQGLGIEFFLGLLLVLVVFGACDPH-KPDSRYTAPL 169

Human   194 TVGLVVLV--IGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHW-WWVPIVSPLLGSI 255
            .:|:.|.:  :||..  .:|.::||||..|....|.:  |.|       || :|   |.|:||.:
  Fly   170 AIGMAVTLGHLGTIR--YTGASMNPARTVGTAFATDI--WAS-------HWVYW---VGPVLGGV 220

Human   256 AGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKE 290
            |...:|..::  ..:..|..||.......|...:|
  Fly   221 AAALLYTQVL--EAKPVPKVNEASEKYRTHADERE 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP3	NP_004916.1	MIP	23..264	CDD:238204	75/247 (30%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:O14520	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:O14520	215..217		1/1 (100%)
Prip	NP_001246266.1	MIP	12..226	CDD:444743	79/264 (30%)