Protein Alignment AQP3 and Drip

DIOPT Version :10

• Sequence 1: NP_004916.1
• Gene: AQP3 / 360
• HGNCID: 636
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_001260893.1
• Gene: Drip / 36236
• FlyBaseID: FBgn0015872
• Length: 278
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 70/251 - (27%)
• Similarity: 103/251 - (41%)
• Gaps: 37/251 - (14%)

Human    20 RLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNP 84
            ::.|..|.|.:||..|:..|.||.        |.|....|...||..|.......|.:||.|:||
  Fly    21 KIWRMLLGELVGTFFLIFVGVGST--------TSGSVPQIAFTFGLTVATIAQGLGHLSGCHINP 77

Human    85 AVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSG-PNGTAGIFA 148
            |||.....:.....:|...|.:.|.:||..||.::              ::.:.| ..|..|:.:
  Fly    78 AVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVI--------------KVALDGVAGGDLGVSS 128

Human   149 TYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYA 213
            ..||  |:.......:.:.|..|:..|.|:.||....: :|.....|||.:..........||.:
  Fly   129 FDPS--LNCAQAVLIEALITFILVFVVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGAS 190

Human   214 VNPARDFGPRLFTALAGWGSAVFTTGQHW-WWV-PIVSPLLGSIAGVFVYQLMIGC 267
            :||||.|||.:.       ..|:|  .|| :|| ||...||..|....:::|..||
  Fly   191 MNPARSFGPAVV-------QGVWT--YHWVYWVGPIAGGLLAGIIYRLIFKLKKGC 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP3	NP_004916.1	MIP	23..264	CDD:238204	67/243 (28%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:O14520	83..85		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:O14520	215..217		1/1 (100%)
Drip	NP_001260893.1	MIP	23..227	CDD:444743	67/237 (28%)