DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1773 and AgaP_AGAP012817

DIOPT Version :9

Sequence 1:	NP_610512.1	Gene:	CG1773 / 35999	FlyBaseID:	FBgn0033439	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_560999.5	Gene:	AgaP_AGAP012817 / 3292527	VectorBaseID:	AGAP012817	Length:	439	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	76/291 - (26%)
Similarity:	116/291 - (39%)	Gaps:	66/291 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CGVLSNLIPAQRLRRRITGGRKSSLLSQPWMAFLHISGDIEMCRCGGSLLSELFVLTAAHCFKMC 110
            ||..|..:        :..|:.:.|   ||:.|  :....|..:|..:|:||.:|:..|.||:
Mosquito   180 CGTKSETV--------LDNGQPAPL---PWLGF--VLTKEEKVKCVVTLISEWYVVGTASCFE-- 229

  Fly   111 PRSKEIRVWLGELDISSTSDCVTYNYQRVCALPVEEFTIDKWILHEEFNLFYPGYDIALIKLNKK 175
            ...|::|:..|..:......|...|...|||.|.:..:|.:.:.|..|:......:||||:|...
Mosquito   230 KNEKDLRILFGGYEDLLEQKCFERNGSTVCAYPTQSRSIGRVVAHPRFSKNTINDNIALIELQSP 294

  Fly   176 V-VFKDHIRPICLPLTDEL----------LAFTLQLG----QSYMAVGWGRTESRRFANSTMEVH 225
            . ..:.|::|||||:|..|          |||.|..|    ||...|      ...|..|   ||
Mosquito   295 ADTTQPHVKPICLPVTPTLYTNRTENFSVLAFRLTTGTIVDQSVNHV------DPDFCKS---VH 350

  Fly   226 INTEKCTDGRDTSFLCANGDYVDTCTGDSGGPLIWKTTLFGKARTVQ--FGVVSTGSQ------- 281
            |......|..:.|| |.:....|....||         |.|:...:|  ..:|:.|.:
Mosquito   351 IVAGFAIDNEEKSF-CVSVPEEDVANCDS---------LLGQGTPLQEHVSMVNAGERYVLRGFD 405

  Fly   282 ----NCGAGQKA---YYMDVPTYVPWILAKM 305
                .| ||..:   .|::|.:|:.|:|..|
Mosquito   406 LLGLTC-AGDSSIPVLYVNVYSYLDWMLYNM 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	70/270 (26%)
CG1773	NP_610512.1	Tryp_SPc	62..301	CDD:238113	70/269 (26%)
AgaP_AGAP012817	XP_560999.5	Tryp_SPc	<1..150	CDD:238113
		Tryp_SPc	190..430	CDD:214473	70/266 (26%)
		Tryp_SPc	190..430	CDD:304450	70/266 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910