DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1773 and cfb

DIOPT Version :9

Sequence 1:	NP_610512.1	Gene:	CG1773 / 35999	FlyBaseID:	FBgn0033439	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_021324426.1	Gene:	cfb / 30604	ZFINID:	ZDB-GENE-980526-487	Length:	761	Species:	Danio rerio

Alignment Length:	294	Identity:	71/294 - (24%)
Similarity:	116/294 - (39%)	Gaps:	104/294 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CGVLSNLIPAQRLRRRITGGRKSSLLSQPWMAFLHISGDIEMCRCGGSLLSELFVLTAAHCFKMC 110
            ||:..|          ..|..|.|  :.||:|.|.|: ..::..|.|||::..::||||||||..
Zfish   467 CGMQQN----------YDGSNKRS--AYPWLAQLSIA-QSQISDCMGSLVTSRYILTAAHCFKEG 518

  Fly   111 PRSKEIRVWLGE-LDISSTSDCVTYNYQRVCALPVEEFTIDKWILHEEFNL----------FYPG 164
            ....:|.|:|.: .|:.                      ::|..:|..::|          || .
Zfish   519 DTPDKITVYLEKNTDVK----------------------VEKVFIHPNYSLTAKQSIGIKEFY-D 560

  Fly   165 YDIALIKLNKKVVFKDHIRPICLP-------------------------LTDELL--AFTLQLGQ 202
            :|:||::|...|....::||||||                         |::||:  |||.::..
Zfish   561 FDVALLQLKTPVKMSVNLRPICLPCTKETNRALKLSDSQGTCEKHEQILLSNELVDAAFTSKMDM 625

  Fly   203 SYMAVGWGRTESRRFANSTMEVHINTEKC---------------TDGRDTSFLCANGDYVD---- 248
            .       :...|:....|:::....:.|               |:....:|||:.|:...
Zfish   626 E-------KRSPRKIRRITVKLGKYLDACVEDAKKAKGIEVADATEAVTKNFLCSGGNQPQRDDV 683

  Fly   249 TCTGDSGGPLIWKTTLFGKARTVQFGVVSTGSQN 282
            :|.|:|||    .|.:....|.:|.||||.|.:|
Zfish   684 SCKGESGG----ATHVDKYGRLIQIGVVSWGVKN 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	68/279 (24%)
CG1773	NP_610512.1	Tryp_SPc	62..301	CDD:238113	68/278 (24%)
cfb	XP_021324426.1	CCP	95..150	CDD:153056
		CCP	157..210	CDD:153056
		vWA_complement_factors	257..455	CDD:238747
		Tryp_SPc	478..710	CDD:238113	65/268 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910