DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1773 and SCRASP1

DIOPT Version :9

Sequence 1:	NP_610512.1	Gene:	CG1773 / 35999	FlyBaseID:	FBgn0033439	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_315638.3	Gene:	SCRASP1 / 1276311	VectorBaseID:	AGAP005625	Length:	1322	Species:	Anopheles gambiae

Alignment Length:	337	Identity:	92/337 - (27%)
Similarity:	146/337 - (43%)	Gaps:	71/337 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GILC-LSCPPSSQAGREDWT-PHELLAYEQLTQQ----DCGVLSNLIPAQRLRR-----RITGGR 66
            |:.| :..|..::|.|...| |:....:.:.:::    .||   .::....||:     |:..|.
Mosquito  1022 GVRCGVYVPTKARAARLRATRPNPRFDFVERSRKIHPDTCG---RVLIDPTLRKPTYGARVVHGS 1083

  Fly    67 KSSLLSQPWMAFLHISGDIEMCRCGGSLLSELFVLTAAHCFKMCPRSKEIRVWLGELDISSTSDC 131
            ::.....||.|.|.:.   .|..||..|::...|||||||....|:| ..||.:|:...::
Mosquito  1084 ETVYGHHPWQASLRVK---TMHWCGAVLITRYHVLTAAHCLIGYPKS-TYRVRIGDYHTAA---- 1140

  Fly   132 VTYNYQRVCALPVEEFTIDKWILHEEFNLFYPGY----DIALIKLNKKVVFKDHIRPICLPLTDE 192
              |:...:      :..|:...:||:|.   .|:    |||::.|...|.|.|:::|||||..|.
Mosquito  1141 --YDNAEL------DIFIENTYIHEQFR---EGHHMSNDIAVVVLKTPVRFNDYVQPICLPARDA 1194

  Fly   193 LLAFTLQLGQSYMAVGWGRTESRRFANSTMEVHINT------------EKCTDGRDTSFLCAN-- 243
                ....||:....|||.||:.. .:|:.::...|            |...|.......||.
Mosquito  1195 ----PYLPGQNCTISGWGATEAGS-KDSSYDLRAGTVPLLPDSVCRRPEVYGDSLIDGMFCAGTL 1254

  Fly   244 --GDYVDTCTGDSGGPLIWKTTLFGKARTVQFGVVSTGSQNCG-AGQKAYYMDVPTYVPWILAKM 305
              |  ||:|.|||||||:...:   :......|:||.| ::|| |.:...|:.|..|..||..|:
Mosquito  1255 EPG--VDSCDGDSGGPLVCPNS---EGLHTLTGIVSWG-KHCGYANKPGVYLKVAHYRDWIEQKL 1313

  Fly   306 AELSDFKGSLHR 317
            .:      |||:
Mosquito  1314 NQ------SLHQ 1319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	75/260 (29%)
CG1773	NP_610512.1	Tryp_SPc	62..301	CDD:238113	74/259 (29%)
SCRASP1	XP_315638.3	ChtBD2	181..228	CDD:214696
		ChtBD2	289..334	CDD:214696
		LDLa	731..762	CDD:238060
		SRCR	776..878	CDD:278931
		SR	776..877	CDD:214555
		LDLa	884..921	CDD:238060
		SR	927..1025	CDD:214555	1/2 (50%)
		SRCR	932..1025	CDD:278931	1/2 (50%)
		Tryp_SPc	1078..1309	CDD:214473	75/260 (29%)
		Tryp_SPc	1079..1312	CDD:238113	76/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910