DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1773 and AgaP_AGAP003686

DIOPT Version :9

Sequence 1:	NP_610512.1	Gene:	CG1773 / 35999	FlyBaseID:	FBgn0033439	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_313469.4	Gene:	AgaP_AGAP003686 / 1274361	VectorBaseID:	AGAP003686	Length:	368	Species:	Anopheles gambiae

Alignment Length:	273	Identity:	82/273 - (30%)
Similarity:	129/273 - (47%)	Gaps:	42/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DCGVLSNLIPAQRLRRRITGGRKSSLLSQPWMAFL-HISG--DIEMCRCGGSLLSELFVLTAAHC 106
            :||:...:       .:|..|:::.|...||||.: ::|.  ..|...|.|::::..:|||||||
Mosquito   118 NCGLPGTV-------NKIAFGQQARLFQYPWMAMIVYVSNTTGTESSECAGTIINVRYVLTAAHC 175

  Fly   107 FK-MCPRSKEIRVWLGELDISSTSDCVTYNYQRVCALPVEEFTIDKWILHEEF-NLFYPGYDIAL 169
            .. ...|.:.:|:  ||.|..:..||    .:..||.|::.:.::..|.|..| .:...|:||.|
Mosquito   176 IDGQMERMRYVRI--GEYDTRTDPDC----EEDTCAAPIQRYGVEDAIFHPNFTRIVRSGHDIGL 234

  Fly   170 IKLNKKVVFKD-HIRPICLPLTDELLAFTLQLGQSYMAVGWGRTESRRFANSTMEVHINTEKCTD 233
            ::||:.:.|.. .:.|:|||.|..|:.|...|   |...|||.||....:...::..|....|:
Mosquito   235 LRLNRSIDFSSGDVSPVCLPFTTGLMGFDPTL---YWITGWGLTERLEVSPVLLQARIPPVSCS- 295

  Fly   234 GRDTSFLCAN-GDYVDTCTGDSGGPLIWKTTLFGKA-------RTVQFGVVSTGSQNCGA-GQKA 289
             ..:..:||. |:....|.||||||:        ||       |.||:||:|.|.: ||. |...
Mosquito   296 -LSSYAICAGFGNATLHCEGDSGGPM--------KAQVPEYNFRFVQYGVISAGPR-CGTQGVPG 350

  Fly   290 YYMDVPTYVPWIL 302
            ....|..::.|||
Mosquito   351 ISSRVSFFMQWIL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	77/254 (30%)
CG1773	NP_610512.1	Tryp_SPc	62..301	CDD:238113	77/253 (30%)
AgaP_AGAP003686	XP_313469.4	CLIP	16..75	CDD:288855
		Tryp_SPc	131..362	CDD:214473	76/250 (30%)
		Tryp_SPc	131..362	CDD:238113	76/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25819
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	1	0.960	-	-
	5	4.780