DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1773 and C2

DIOPT Version :9

Sequence 1:	NP_610512.1	Gene:	CG1773 / 35999	FlyBaseID:	FBgn0033439	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_038512.2	Gene:	C2 / 12263	MGIID:	88226	Length:	760	Species:	Mus musculus

Alignment Length:	378	Identity:	91/378 - (24%)
Similarity:	146/378 - (38%)	Gaps:	104/378 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LGITALIWGILCLSCPPSSQAG-REDWTPHELLAYEQLTQQDCGVLSNLIPAQRLRRRITG-GRK 67
            |.|.|:..|.|.:.....::.| ::|...|..:..:....|.  :..:::...:|...|.| |..
Mouse   413 LDIYAIGVGKLDVDWKELNELGSKKDGERHAFILQDAKALQQ--IFEHMLDVSKLTDTICGVGNM 475

  Fly    68 SSLLSQ----PW-MAFLHISGDIEMCRCGGSLLSELFVLTAAHCFKMCPRSKEIRVWLGEL-DIS 126
            |:..|.    || :.|...|.:    .|.|||:|:.:||||||||... :.::..:|...: |.:
Mouse   476 SANASDQERTPWQVTFKPKSKE----TCQGSLISDQWVLTAAHCFHDI-QMEDHHLWRVNVGDPT 535

  Fly   127 STSDCVTYNYQRVCALPVEEFTIDKWILHEEFNL----------FYPGYDIALIKLNKKVVFKDH 181
            |...              :||.::..|:...||:          ||.. ||||:||::||....|
Mouse   536 SQHG--------------KEFLVEDVIIAPGFNVHAKRKQGISEFYAD-DIALLKLSRKVKMSTH 585

  Fly   182 IRPICLPLT-------------------DELLA-----------------FTLQLGQSYMAVGWG 210
            .||||||.|                   .|||:                 ..|:.|..:......
Mouse   586 ARPICLPCTVGANMALRRSPGSTCKDHETELLSQQKVPAHFVALNGNRLNINLRTGPEWTRCIQA 650

  Fly   211 RTESRRFANSTMEVHINTEKCTDGRDTSFLCANGDYVD--TCTGDSGGPLIWKTTLFGKARTVQF 273
            .::::....|...|   :|..||    .|||:..:..|  .|.|:|||.:.    |..:.|..|.
Mouse   651 VSQNKNIFPSLTNV---SEVVTD----QFLCSGMEEEDDNPCKGESGGAVF----LGRRYRFFQV 704

  Fly   274 GVVS-------TGSQNCGAGQKA--------YYMDVPTYVPWILAKMAELSDF 311
            |:||       .||.|....:|.        :::.:....||:...:..:.||
Mouse   705 GLVSWGLFDPCHGSSNKNLRKKPPRGVLPRDFHISLFRLQPWLRQHLDGVLDF 757

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	78/309 (25%)
CG1773	NP_610512.1	Tryp_SPc	62..301	CDD:238113	78/308 (25%)
C2	NP_038512.2	CCP	94..149	CDD:153056
		CCP	156..210	CDD:214478
		vWFA	260..457	CDD:294047	9/45 (20%)
		MIDAS-like motif. /evidence=ECO:0000250	267..271
		Tryp_SPc	480..750	CDD:238113	75/300 (25%)
		Tryp_SPc	480..721	CDD:214473	71/271 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7585
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860