Protein Alignment CG1773 and KLK8

DIOPT Version :10

• Sequence 1: NP_610512.1
• Gene: CG1773 / 35999
• FlyBaseID: FBgn0033439
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 80/279 - (28%)
• Similarity: 115/279 - (41%)
• Gaps: 63/279 - (22%)

  Fly    47 GVLSNLIP-----AQRLRRRITGGRKSSLLSQPWMAFLHISGDIEMCRCGGSLLSELFVLTAAHC 106
            |..||.:|     ::....::.||.:....||||.|.| ..|  :...|||.|:...:|||||||
Human    58 GWRSNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAAL-FQG--QQLLCGGVLVGGNWVLTAAHC 119

  Fly   107 FKMCPRSKEIRVWLGELDISSTSDCVTYNYQRVCALPVEEFTIDKWILH--------EEFNLFYP 163
                 :..:..|.||:..:.:...            |.:|..:.:.|.|        |:.|
Human   120 -----KKPKYTVRLGDHSLQNKDG------------PEQEIPVVQSIPHPCYNSSDVEDHN---- 163

  Fly   164 GYDIALIKLNKKVVFKDHIRPICLPLTDELLAFTLQLGQSYMAVGWGRTESRR--FAN--STMEV 224
             :|:.|::|..:......::||      .|.....|.||.....|||...|.|  |.:  :..||
Human   164 -HDLMLLQLRDQASLGSKVKPI------SLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEV 221

  Fly   225 HI-NTEKCTD---GRDT-SFLCANGDY-VDTCTGDSGGPLIWKTTLFGKARTVQFGVVSTGSQNC 283
            .| ..:||.|   |:.| ..:||.... .|||.|||||||:....|        .|:.|.||..|
Human   222 KIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGAL--------QGITSWGSDPC 278

  Fly   284 GAGQK-AYYMDVPTYVPWI 301
            |...| ..|.::..|:.||
Human   279 GRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	74/258 (29%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	74/258 (29%)