| Sequence 1: | NP_477310.2 | Gene: | Uba1 / 35998 | FlyBaseID: | FBgn0023143 | Length: | 1191 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003959.3 | Gene: | UBA3 / 9039 | HGNCID: | 12470 | Length: | 463 | Species: | Homo sapiens |
| Alignment Length: | 650 | Identity: | 128/650 - (19%) |
|---|---|---|---|
| Similarity: | 211/650 - (32%) | Gaps: | 293/650 - (45%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 596 KKFQEK------------------LADS-KWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMD 641
Fly 642 LIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGV 706
Fly 707 ANALDNVDARIYMDRKCI------------FNRIPLVETGTLGTLGNVQVIVPFATESYSSSQD- 758
Fly 759 -PPEKSIPICTLKNFPNAIEHTLQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPLEI 822
Fly 823 LDSIKKALIDDKPKSFAHCVEWAR-LYWEDQYVNQIKQLLFNFPPDQITSSGQPFWSGPKRCPDP 886
Fly 887 LVFDVNDPMHLDFIYAAANLRAEVYGIEQVRNRETIAELVQKVKVPEFKPRSGVKIETNEAAAAA 951
Fly 952 SANNFDDGELDQDRVDKIISELLKNADKSSKITPLEFEKDDDSNLHMDFIVACSNLRAANYKIPP 1016
Fly 1017 ADRHKSKLIAGKIIPAIATTTSVLSGLAVLEVIKLIVGHRDLVKFKNGFANLALPFMAFS----- 1076
Fly 1077 ----------EPLPAAKNTYYGKEWTLWDRFEVTGELSLQEFLNYFEENEKLK-----ITMLSQG 1126
Fly 1127 VSMLYSFFMPKAKCSERLPLPMSEVVRRVSKRRLEPHERSLVFEICCNDVDGEDVEVPYVRYTLP 1191 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Uba1 | NP_477310.2 | Ube1 | 194..1188 | CDD:273603 | 126/645 (20%) |
| Ube1_repeat1 | 199..574 | CDD:238768 | |||
| E1_4HB | 447..510 | CDD:292809 | |||
| Ube1_repeat2 | 606..1144 | CDD:238767 | 113/572 (20%) | ||
| UBA3 | NP_003959.3 | Interaction with UBE2M N-terminus | 53..70 | 2/16 (13%) | |
| Uba3_RUB | 71..368 | CDD:238765 | 102/506 (20%) | ||
| Interaction with UBE2M N-terminus | 157..161 | 0/3 (0%) | |||
| Interaction with UBE2M N-terminus | 192..217 | 10/24 (42%) | |||
| Interaction with NEDD8 | 227..229 | 0/1 (0%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 242..248 | 3/67 (4%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 292..295 | 2/96 (2%) | |||
| Interaction with UBE2M N-terminus | 331..338 | 0/8 (0%) | |||
| Interaction with NEDD8 | 352..357 | 0/4 (0%) | |||
| Interaction with UBE2M core domain | 368..463 | 19/113 (17%) | |||
| E2_bind | 376..461 | CDD:400951 | 18/97 (19%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0476 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||