Protein Alignment Uba1 and ULA1

DIOPT Version :10

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_015322.1
• Gene: ULA1 / 856104
• SGDID: S000005924
• Length: 462
• Species: Saccharomyces cerevisiae
• Alignment Length: 549
• Identity: 97/549 - (17%)
• Similarity: 184/549 - (33%)
• Gaps: 163/549 - (29%)

  Fly   586 RYDSQIAIFGKKFQEKLADSKWFIVG-AGAIGCELLKNFGMLGLGT----------GNGQIFVTD 639
            |||.|:.::|...|:.|..|:..:|| |..:..|:.||..:.|:.:          .:|.:|:.:
Yeast     3 RYDRQLRLWGALGQDSLNRSRVCVVGPATPLLQEVFKNLVLAGISSLTWLKVECAVQSGSLFLAE 67

  Fly   640 MDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYEL----RVGAETEKVFSEDFF 700
            :....:...::|..:..:|::|          ....|:.:.|.:.:    .:|.:|.
Yeast    68 LKKDLEPLASKQLEYEENDLRK----------TLQQPQYDWTRFSVVILTCIGEQTA-------- 114

  Fly   701 GKLDGVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIP 765
                    .||..:.|.....|.    .|::.|...|..|.:.:::   :|::...|..|:....
Yeast   115 --------MLDLNEIRRQRGTKF----PPVLNTFVSGFYGYIYLVL---SETHFVLQAHPDSKKY 164

  Fly   766 ICTLKN-FPNAIEHTLQWARDAFEGVFKQSAENAAQYIADPQ---FTERIAKL--PGIQPLEILD 824
            ...|:| :|..|.:.     |.|:    .|..:.|.:...|.   ..:.||||  .|......:|
Yeast   165 DLRLQNPWPELINYV-----DTFD----LSKMDTATFSGIPYTVLLMKCIAKLERDGNNGRITID 220

  Fly   825 SIKKAL-----------------IDDKPKSFAHCVEWARLYWEDQYVNQIKQLLFNFPPDQITSS 872
            .:||.|                 ::.|..::..|.       ::....:::.||.|..
Yeast   221 QMKKVLDQICLPLGNDVIYEPNYVEAKRYAYLACS-------QNDCCKELEDLLRNLE------- 271

  Fly   873 GQPFWSGPKRCPDPLVFDVNDPMHLDFIYAAANLRAEVYGIEQVRNRETIAELVQKVKVPEFKPR 937
                           :.|..:..|            :.|..|.:....|:..:.::.....|:|.
Yeast   272 ---------------ISDYGNDWH------------DTYNYEILTLLLTLKNIAKENGELSFQPL 309

  Fly   938 SGVKIETNEAAAAASANNF--------DDGELDQDRVD-------KIISE-----LLKNADKSSK 982
            :|...:..     ::..|:        ...:||:.||:       ||:|:     ...:..:..|
Yeast   310 TGTLPDME-----STTENYIRLKKLYEVKAKLDKSRVEESLARSKKIVSQDVLETFCSHYGEVRK 369

  Fly   983 ITPLEFEKDD------DSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIATTTSVLS 1041
            |.|   .|.|      .||..:|.:|     ....::.|...........|..:....:..:...
Yeast   370 ILP---PKSDLLGIFSTSNALLDALV-----MVQFWEQPAVTAEDKDEFIGLRVDDNYSVMAFFG 426

  Fly  1042 GLAVLEVIKLIVGHR---DLVKFKNGFAN 1067
            |..|.|.||||..|.   |.:...||..|
Yeast   427 GAVVQEAIKLITHHYVPIDNLFLYNGINN 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	97/549 (18%)
ULA1	NP_015322.1	E1_enzyme_family	2..460	CDD:451392	97/549 (18%)