DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba1 and Mocs3

DIOPT Version :9

Sequence 1:	NP_477310.2	Gene:	Uba1 / 35998	FlyBaseID:	FBgn0023143	Length:	1191	Species:	Drosophila melanogaster
Sequence 2:	NP_001153802.1	Gene:	Mocs3 / 69372	MGIID:	1916622	Length:	460	Species:	Mus musculus

Alignment Length:	220	Identity:	64/220 - (29%)
Similarity:	99/220 - (45%)	Gaps:	14/220 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   586 RYDSQIAI--FGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNL 648
            ||..|:.:  .|.:.|.:||.:...:||.|.:||.|.:.....|:    |::.:.|.|::|.|||
Mouse    62 RYSRQLLLPELGVRGQLRLAAAAVLVVGCGGLGCPLAQYLAAAGV----GRLGLVDHDVVETSNL 122

  Fly   649 NRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNV 713
            .||.|.......:.|:.:||.|::|:|..|...||. |..||.   ::.|.....|.||:..|||
Mouse   123 ARQVLHGEAQAGESKARSAAAALRRLNSAVECVAYP-RALAED---WALDLVRGYDVVADCCDNV 183

  Fly   714 DARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSS--SQDPPEKSIPICTLKNFPNAI 776
            ..|..::..|:....|||....|...|.:.|........|..  .:.||.:::..|.......|:
Mouse   184 PTRYLVNDACVLAGRPLVSASALRFEGQMTVYHHDGGPCYRCVFPRPPPPETVTNCADGGVLGAV 248

  Fly   777 EHTLQWARDAFEGVFKQSAENAAQY 801
            ...|..|: |.| |.|.:|...:.|
Mouse   249 PGVLGCAQ-ALE-VLKIAAGLGSSY 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	64/220 (29%)
		Ube1_repeat1	199..574	CDD:238768
		E1_4HB	447..510	CDD:292809
		Ube1_repeat2	606..1144	CDD:238767	57/198 (29%)
Mocs3	NP_001153802.1	PRK07411	56..460	CDD:180967	64/220 (29%)
		ThiF_MoeB_HesA_family	62..285	CDD:238386	64/220 (29%)
		RHOD_ThiF	327..460	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810