Protein Alignment Uba1 and Sae1

DIOPT Version :9

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_001272820.1
• Gene: Sae1 / 56459
• MGIID: 1929264
• Length: 350
• Species: Mus musculus
• Alignment Length: 430
• Identity: 107/430 - (24%)
• Similarity: 155/430 - (36%)
• Gaps: 145/430 - (33%)

  Fly   192 GGDIDE---SLYSRQLYVLGHDAMRRMANSDILLSGLGGLGLEIAKNVILGGVKSITLHDTATCG 253
            ||.|.|   :.|.||:.:.|.:|.:|:..|.:|:.|:.|||.|||||:||.|||.:|:.|.....
Mouse    12 GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVS 76

  Fly   254 LHDLSSQFYLTEADIGKNRAEASCAQLAELNNYVRTVSHTGPL---TEEFLRKFRVVVLTNSDGE 315
            ..|..:||.:....:|:||||||..:...||..|.....|..:   .|.|..||..|.||....:
Mouse    77 PEDPGAQFLIQTGSVGRNRAEASLERAQNLNPMVDVKVDTEDVEKKPESFFTKFDAVCLTCCSRD 141

  Fly   316 EQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPISTMIASITHDAQGVVTCL 380
            ...::.:..|.|.|.....:..|.....|.:.||...:.::       |.:|.:   :|||
Mouse   142 VIIKVDQICHRNSIKFFTGDVFGYHGYTFANLGEHEFVEEK-------TKVAKV---SQGV---- 192

  Fly   381 DETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTFSIGDTSKFGEYKSGGVATQVKMPKT 445
                   .||
Mouse   193 -------EDG------------------------------------------------------- 195

  Fly   446 ISFKPLAQATEEPEFLISDFAKLDSPATLHVAFNALSCYRKAHNGALPRPWNEEDANS------- 503
                        ||   :..|||||..|..|....|.|..|.   ||...|:.|.|.:
Mouse   196 ------------PE---AKRAKLDSSETTMVKKKVLFCPVKE---ALEVDWSGEKAKAALKRTAP 242

  Fly   504 ---FLEVV----------RASSNAEVDEKLVLQ-------------------FAKICSGNTCPLD 536
               .|:|:          ..|.:.:.|.:|:||                   |.:.|.....|:.
Mouse   243 DYFLLQVLLKFRTDKGRDPTSESYKEDAELLLQIRNDVFDSLGISPDLLPDDFVRYCFSEMAPVC 307

  Fly   537 AAVGGIVAQEVLKACSGKFTPIYQWLYFDAL------ECL 570
            |.||||:|||::||.|.:..|...:.:||.:      |||
Mouse   308 AVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECL 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	105/428 (25%)
		Ube1_repeat1	199..574	CDD:238768	103/420 (25%)
		E1_4HB	447..510	CDD:292809	19/82 (23%)
		Ube1_repeat2	606..1144	CDD:238767
Sae1	NP_001272820.1	Aos1_SUMO	20..345	CDD:238769	100/418 (24%)
		ThiF	23..338	CDD:279270	100/408 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810