Protein Alignment Uba1 and Uba2

DIOPT Version :9

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 477
• Identity: 142/477 - (29%)
• Similarity: 219/477 - (45%)
• Gaps: 81/477 - (16%)

  Fly   593 IFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNRQFLFRPH 657
            :|....||.:..||..:||||.||||:|||..:    :|...|.:.|:|.|:.|||||||||...
  Fly     8 VFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVL----SGFTDIEIIDLDTIDLSNLNRQFLFHRE 68

  Fly   658 DVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARIYMDRK 722
            .|.|.|:..|.::....||:..:|||...|   |...:..:||.|.|.|.:||||..||.:::|.
  Fly    69 HVGKSKARVARESALSFNPDAKITAYHDSV---TSTDYGVNFFKKFDLVLSALDNRAARNHVNRM 130

  Fly   723 CIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAF 787
            |:...:||:|:||.|..|.|::|....|:.|..:....::|.|.||::|.|:...|.:.||:..|
  Fly   131 CLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLF 195

  Fly   788 EGVFKQSA--ENAAQYIADPQFTERIA-------KLPGIQPLEILDSIKKALIDDKPKSF--AHC 841
            ..:|.:|.  |:.:...|||...|:..       |..|.:..|.....|:|..|....:.  .:.
  Fly   196 NQLFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINT 260

  Fly   842 VEWARLYWEDQYVNQIKQLLFN-FPPDQIT-----SSGQPFWSGPKRCPDPLVFDVNDPMHLDFI 900
            .:||:      ..|.....||| |..:.||     |:   .|. .::.|.|:.:|
  Fly   261 RQWAK------DCNYDAGKLFNKFFNEDITYLLRMSN---LWK-TRKAPVPVQWD---------- 305

  Fly   901 YAAANLRAEVYGIEQVRNRETIAELVQKVKVPEFKPRSGVKIETNEAAAAASANNFDDGELDQDR 965
                .|..|....:|    :.:|             :...|:.:.|..|...||:
  Fly   306 ----TLLPEGSSGDQ----KDVA-------------KQHHKVWSIEECAQVFANS---------- 339

  Fly   966 VDKIISELLKNADKSSKITPLEFEKDDDSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKII 1030
                :.||..|..|......|.::|||..  .|||:.||:|:|:..:.|....|.:.|.:||.||
  Fly   340 ----LKELSANFLKLEGDDTLAWDKDDQP--AMDFVAACANVRSHIFDIERKSRFEIKSMAGNII 398

  Fly  1031 PAIATTTSVLSGLAVLEVIKLI 1052
            ||||||.::.:|::|:...|::
  Fly   399 PAIATTNAITAGISVMRAFKVL 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	142/477 (30%)
		Ube1_repeat1	199..574	CDD:238768
		E1_4HB	447..510	CDD:292809
		Ube1_repeat2	606..1144	CDD:238767	138/464 (30%)
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	68/175 (39%)
		Uba2_SUMO	21..459	CDD:238766	138/464 (30%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840