Protein Alignment Uba1 and APP-BP1

DIOPT Version :10

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 99/545 - (18%)
• Similarity: 197/545 - (36%)
• Gaps: 140/545 - (25%)

  Fly   586 RYDSQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNR 650
            :||.||.::|:..|..|..:...:|...|:|||..|...:.|:    |...|.|...:::.:|..
  Fly    17 KYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGI----GGFTVADGSTVKEEDLGN 77

  Fly   651 QFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLD-GVANALDNVD 714
            .|......:.|.|::.....::.:||:||....:  ..|:.......:||...| .:|:.|:...
  Fly    78 NFFLDSSYLGKSKALACMQLLQELNPDVNGDYVD--ESADFLLANRPNFFDSFDLVIASNLNEQT 140

  Fly   715 ARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHT 779
            ..:..:|....| :||:...:||.||.:::.:    ..:...:..|:.       :.|...:||.
  Fly   141 LLLLAERLWELN-VPLIYCRSLGMLGTIRLQI----REHCIVEAHPDN-------RQFDLRLEHP 193

  Fly   780 LQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPL------------------------ 820
            ....|:..:|                  ||..:|:|.:..|
  Fly   194 FDALREHLDG------------------TEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEK 240

  Fly   821 -EILDSIKKALIDDKPKSFAHCVEWAR-LYWEDQYVNQIKQLLFNFPPDQITSSGQPFW------ 877
             ::.::|::.:..|: :::...::... .:...|....:|.:..:...:|:......||
  Fly   241 NQLKETIREEMKADE-ENYEEAIKAVNTAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKAL 304

  Fly   878 --------SG----PKRCPDPLVFDVNDPMHLDFIYAAANLRAEVYGIEQVRNRETIAELVQKVK 930
                    .|    |...|| :..:.:..:.|..||....|:    ..:||.::  ..|.::::.
  Fly   305 KHFVIHENEGHLPLPGVLPD-MTANTDSYIALQHIYRQQALQ----DADQVYHK--CQEYLKQLA 362

  Fly   931 VP--EFKPRSGVKIETNEAAAAASANNFDDGELDQDRVDKIISELLKNADKSSKITPLEFEKDDD 993
            :|  ....|| |::...|||..|....               :.:.:..:|||::.||..:.:..
  Fly   363 LPADSIDERS-VRLICKEAAGLAVIRG---------------TRIAEEYEKSSRLLPLVEDNELQ 411

  Fly   994 SNL---------HMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIA--------------- 1034
            .||         :..|:..|.|:  ....|...|..:.|.||.|::..:.
  Fly   412 GNLTAYNFALRAYERFLSECGNI--PGECIVEQDIGRLKSIAAKMLSDLGMHATISDDVLHEICR 474

  Fly  1035 -------TTTSVLSGLAVLEVIKLI 1052
                   ..::.:.|.|..||||:|
  Fly   475 YGGAELHAVSAFIGGCAAQEVIKII 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	99/545 (18%)
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	99/545 (18%)