DRSC/TRiP Functional Genomics Resources

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Protein Alignment Uba1 and uba5

DIOPT Version :10

Sequence 1:NP_477310.2 Gene:Uba1 / 35998 FlyBaseID:FBgn0023143 Length:1191 Species:Drosophila melanogaster
Sequence 2:NP_001292546.1 Gene:uba5 / 386712 ZFINID:ZDB-GENE-031112-2 Length:398 Species:Danio rerio


Alignment Length:340 Identity:67/340 - (19%)
Similarity:123/340 - (36%) Gaps:104/340 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   575 VEEADAQPVGSRYDSQIAIFGK----KFQEKLADSKWFIVGAGAIG---CELLKNFGMLGLGTGN 632
            :|:..|:.|.|...|::....:    :..||:......:||.|.:|   .|:|...|:       
Zfish    36 IEQMSAEVVDSNPYSRLMALKRMGIVQDYEKIRSFAVAVVGVGGVGSVTAEMLTRCGI------- 93

  Fly   633 GQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEV-------------NVTAYE 684
            |::.:.|.|.:|.:|:||.| |:||.....|...|...::.:||:|             |.|.:.
Zfish    94 GKLLLFDYDKVELANMNRLF-FQPHQAGLSKVEAAQHTLRNINPDVAFETHNYNITTMDNFTHFM 157

  Fly   685 LRV---GAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLV--ETGTL--GTLGNV 742
            .||   |.|..|        .:|.:.:.:||.:||:.::..|  |.:..:  |:|..  ...|::
Zfish   158 DRVSHGGLEEGK--------PVDLILSCVDNFEARMAINTAC--NELGQIWMESGVSENAVSGHI 212

  Fly   743 QVIVP------------------------------------------------------FATESY 753
            |:|:|                                                      |.|.||
Zfish   213 QLIIPGETACFACAPPLVVAANIDEKTLKRDGVCAASLPTTMGVVAGLLVQNVLKYLLGFGTVSY 277

  Fly   754 SSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQ 818
            ....:..:...|...:|..|...:...:..:|.::   |:.||...|.:.  |..|.:.......
Zfish   278 YLGYNAMQDFFPSMAMKANPQCDDRHCRRQQDEYK---KKEAERPKQEVV--QEEEEVVHEDNEW 337

  Fly   819 PLEILDSIKKALIDD 833
            .:|::..:.:|.:.|
Zfish   338 GIELVSEVTEAELQD 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Uba1NP_477310.2 Ube1 194..1188 CDD:273603 67/340 (20%)
uba5NP_001292546.1 ThiF_MoeB_HesA_family 48..293 CDD:238386 51/262 (19%)
UFM1-interacting sequence (UIS). /evidence=ECO:0000250|UniProtKB:Q9GZZ9 330..342 1/11 (9%)
Linker. /evidence=ECO:0000250|UniProtKB:Q9GZZ9 343..373 2/10 (20%)
UFC1-binding sequence (UFC). /evidence=ECO:0000250|UniProtKB:Q9GZZ9 383..398
Blue background indicates that the domain is not in the aligned region.

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