Protein Alignment Uba1 and Uba1

DIOPT Version :10

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_552371.4
• Gene: Uba1 / 3291445
• VectorBaseID: AGAMI1_003109
• Length: 1105
• Species: Anopheles gambiae
• Alignment Length: 1113
• Identity: 712/1113 - (63%)
• Similarity: 861/1113 - (77%)
• Gaps: 47/1113 - (4%)

  Fly   103 AEKQKLKQSQGSGDDVSTSSAVEKEGSKRPEKRNYLNTTTIESQEASSSAS------ATSNSNNN 161
            |:|:||...       :.|.....|..::|.:..:.::..||....||:|:      ||||:|.:
Mosquito    16 AKKRKLPSP-------TPSLTQPPEHEQQPSQPPHSSSPAIERSAPSSAAAAAVVVMATSNNNGS 73

  Fly   162 --VSSSNNNSNNSTNNRQLEGSSNMAGNSAAAGG--DIDESLYSRQLYVLGHDAMRRMANSDILL 222
              |.|..|||               ||.....||  :|||.||||||||||||||||||.||:|:
Mosquito    74 APVPSVENNS---------------AGGGGGGGGAQEIDEGLYSRQLYVLGHDAMRRMARSDVLI 123

  Fly   223 SGLGGLGLEIAKNVILGGVKSITLHDTATCGLHDLSSQFYLTEADI--GKNRAEASCAQLAELNN 285
            |||||||:|:|||||||||||:||||||.|.:.|||||||||..|:  |:|||||||.||:|||:
Mosquito   124 SGLGGLGVEVAKNVILGGVKSVTLHDTAVCTVGDLSSQFYLTAEDVAGGRNRAEASCQQLSELNH 188

  Fly   286 YVRTVSHTGPLTEEFLRKFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGES 350
            ||.||::||.||||||:||||||||.:...||:|:|:..|.:.||||:|:||||||:||||||..
Mosquito   189 YVPTVAYTGELTEEFLQKFRVVVLTLAPPAEQRRVAEITHRHNIALIVADTRGLFAQVFCDFGVD 253

  Fly   351 FTIYDQDGTQPISTMIASITHDAQGVVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVL 415
            ||:|||:|..|.|.|:||||:||:.:|||:|||||||.|||||||:|||||.|||||.|:||.||
Mosquito   254 FTVYDQNGANPSSAMVASITNDAESLVTCVDETRHGFEDGDYVTFTEVQGMTELNGCAPMKIKVL 318

  Fly   416 GPYTFSIGDTSKFGEYKSGGVATQVKMPKTISFKPLAQATEEPEFLISDFAKLDSPATLHVAFNA 480
            ||||||||||||...|..||:||||||.|.:|||.||:|...|||:::||||.|.||...:||..
Mosquito   319 GPYTFSIGDTSKLSPYLRGGIATQVKMSKQMSFKSLAEAENAPEFIMTDFAKWDHPANTQIAFTV 383

  Fly   481 LSCYRKAHNGALPRPWNEEDANSFLEVVRASSN----AEVDEKLVLQFAKICSGNTCPLDAAVGG 541
            |..|::.| |.||||||.|||..|:|:.|..:.    .|::|.::.:|||:|:|:.||::.|:||
Mosquito   384 LGRYQEQH-GRLPRPWNVEDAAEFVEMCRKRAKEMGVEELNEAMLTKFAKVCAGDLCPMNGAIGG 447

  Fly   542 IVAQEVLKACSGKFTPIYQWLYFDALECLPTEGVEEADAQPVGSRYDSQIAIFGKKFQEKLADSK 606
            |.||||:|||:||||||.|:|.:||||||....:.|.:..|.|||||.|||:||:|||:.|...|
Mosquito   448 ITAQEVMKACTGKFTPINQYLCYDALECLQEADLTEEECAPTGSRYDGQIAVFGRKFQDVLGQLK 512

  Fly   607 WFIVGAGAIGCELLKNFGMLGLGT-GNGQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADA 670
            :||||||||||||||||.|:|:.: |:|:|.||||||||||||||||||||||||:|||..||.|
Mosquito   513 YFIVGAGAIGCELLKNFAMIGVASKGDGEIIVTDMDLIEKSNLNRQFLFRPHDVQQPKSRVAAQA 577

  Fly   671 IKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLVETGT 735
            :||||.::.||::|.|||.|||:.:.:.||.:||||||||||:||||||||:|::.|.||:|:||
Mosquito   578 VKRMNGDIKVTSHENRVGPETERFYDDTFFNRLDGVANALDNIDARIYMDRRCVYYRKPLLESGT 642

  Fly   736 LGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAFEGVFKQSAENAAQ 800
            ||||||:||:|||.||||||||||||||||||||||||||||||||||||.|||:|||.||||||
Mosquito   643 LGTLGNIQVVVPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDTFEGIFKQVAENAAQ 707

  Fly   801 YIADPQFTERIAKLPGIQPLEILDSIKKALIDDKPKSFAHCVEWARLYWEDQYVNQIKQLLFNFP 865
            ||:||.|.||..||||:||||.|:|:|||||||:|||...||:|||:|:|:||.|||:|||||||
Mosquito   708 YISDPTFIERTLKLPGVQPLEALESVKKALIDDRPKSIEDCVKWARMYFEEQYSNQIRQLLFNFP 772

  Fly   866 PDQITSSGQPFWSGPKRCPDPLVFDVNDPMHLDFIYAAANLRAEVYGIEQVRNRETIAELVQKVK 930
            |||::|:||||||||||.|:.:.||..:|:|||:|:|.|||:||||||.|.|||:.|.::|..::
Mosquito   773 PDQMSSTGQPFWSGPKRLPEAITFDPEEPLHLDYIFATANLKAEVYGIPQQRNRDAIRKIVMTIE 837

  Fly   931 VPEFKPRSGVKIETNEAAAAASANNFDDG-------ELDQDRVDKIISELLKNADKSSKITPLEF 988
            ||:|.|||||||...::|..|..|....|       :||.||:.::.|||.........||||||
Mosquito   838 VPKFTPRSGVKIAVTDSALQAEENGGGGGGGGAGGEDLDPDRIGRLQSELAALGKPDFTITPLEF 902

  Fly   989 EKDDDSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIATTTSVLSGLAVLEVIKLIV 1053
            |||||:|||||||||.|||||||||||||||||||||||||:||||||||:::|.|.||:.||..
Mosquito   903 EKDDDNNLHMDFIVAASNLRAANYKIPPADRHKSKLIAGKIMPAIATTTSLVAGCASLELYKLAQ 967

  Fly  1054 GHRDLVKFKNGFANLALPFMAFSEPLPAAKNTYYGKEWTLWDRFEVTGELSLQEFLNYFEENEKL 1118
            |...|.:|||||.||||||..||||:.|.|.|||.|||||||||||.|||:|||||:|||...||
Mosquito   968 GFNTLERFKNGFLNLALPFFTFSEPIQAKKATYYDKEWTLWDRFEVKGELTLQEFLDYFEREHKL 1032

  Fly  1119 KITMLSQGVSMLYSFFMPKAKCSERLPLPMSEVVRRVSKRRLEPHERSLVFEICCNDVDGEDVEV 1183
            |||||||||.|||:|||.|.|..|||.||||||||:|||:.:|||.|:|||||||||.:||||||
Mosquito  1033 KITMLSQGVCMLYAFFMTKQKQQERLNLPMSEVVRKVSKKSIEPHVRALVFEICCNDEEGEDVEV 1097

  Fly  1184 PYVRYTLP 1191
            |||||.||
Mosquito  1098 PYVRYVLP 1105

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	682/1007 (68%)
Uba1	XP_552371.4	None