Protein Alignment Uba1 and Uba1y

DIOPT Version :10

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_001395667.1
• Gene: Uba1y / 25225
• RGDID: 3925
• Length: 1057
• Species: Rattus norvegicus
• Alignment Length: 1066
• Identity: 606/1066 - (56%)
• Similarity: 770/1066 - (72%)
• Gaps: 31/1066 - (2%)

  Fly   145 SQEASSSASATSNSNNNVSSSNNNSNNSTNNRQLEGSSNMAGNSAAAGGDIDESLYSRQLYVLGH 209
            |....|.....|..::.|.||..::::.........:|.|:.|...   ||||||||||||||||
  Rat     2 SSSVLSKKRRVSGPDSEVDSSWPSTHSVMFGAPPGPNSGMSKNKEM---DIDESLYSRQLYVLGH 63

  Fly   210 DAMRRMANSDILLSGLGGLGLEIAKNVILGGVKSITLHDTATCGLHDLSSQFYLTEADIGKNRAE 274
            :||:.:..|.:|:|||.|||:|||||:||||||::||||..|....||||||||.|.||||||||
  Rat    64 EAMKHLQTSSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLHEEDIGKNRAE 128

  Fly   275 ASCAQLAELNNYVRTVSHTGPLTEEFLRKFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGL 339
            .|..:|||||:||...::||||.::||..|:||||||:..|.|.::.:|.|.:||.|::|:||||
  Rat   129 VSQPRLAELNSYVPVHTYTGPLVDDFLSGFQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGL 193

  Fly   340 FAKVFCDFGESFTIYDQDGTQPISTMIASITHDAQGVVTCLDETRHGFNDGDYVTFSEVQGMQEL 404
            ..::||||||...:.|.:|.||:|.|::.||.:..|:||||:||||||..||:|:|:|||||.||
  Rat   194 VGQLFCDFGEEMILTDANGEQPLSAMVSMITKENPGIVTCLEETRHGFESGDFVSFTEVQGMSEL 258

  Fly   405 NGCQPLKITVLGPYTFSIGDTSKFGEYKSGGVATQVKMPKTISFKPLAQATEEPEFLISDFAKLD 469
            ||..|::|.|||||:|||.|||.|.||..||:.:|||:.:.||||.|..:..||||:|:||||..
  Rat   259 NGIGPMEIKVLGPYSFSICDTSSFSEYTRGGIVSQVKVSQKISFKSLVASLAEPEFVITDFAKCC 323

  Fly   470 SPATLHVAFNALSCYRKAHNGALPRPWNEEDANSFLEVVRASSNAE---------VDEKLVLQFA 525
            .||.||:.|.||..:...|:.. |||.|||||...:.:.:| .||:         :|..|:.:.|
  Rat   324 RPAQLHIGFQALHQFCTQHSRP-PRPHNEEDAAEMVTLAQA-VNAQSLPAVQQDCLDIDLIRKLA 386

  Fly   526 KICSGNTCPLDAAVGGIVAQEVLKACSGKFTPIYQWLYFDALECLPTEGVE--EADAQPVGSRYD 588
            .:.:|:..|:.|.:||:.||||:|||||||.||.||||||||||||...|.  |....|..:|||
  Rat   387 YVAAGDLAPMSAFIGGLAAQEVMKACSGKFMPIRQWLYFDALECLPEHRVAFMEDKCLPRQNRYD 451

  Fly   589 SQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTG-NGQIFVTDMDLIEKSNLNRQF 652
            .|:|:||...||||...|:|:||||||||||||||.|:|||.| .|:|.|||||.||||||||||
  Rat   452 GQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEITVTDMDTIEKSNLNRQF 516

  Fly   653 LFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARI 717
            ||||.||.|.||.|||.|::.:||.:.|.:::.|||.|||.|:.:|||..||||||||||||||:
  Rat   517 LFRPWDVTKLKSETAAAAVRDINPHIRVCSHQNRVGPETEHVYDDDFFQNLDGVANALDNVDARL 581

  Fly   718 YMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQW 782
            ||||:|::.|.||:|:|||||.|||||:|||.|||||||||||||||||||||||||||||||||
  Rat   582 YMDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQW 646

  Fly   783 ARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPLEILDSIKKALIDDKPKSFAHCVEWARL 847
            |||.|||:|||||||..||:.||:|.||..:|.|.||||:|::|:.:|:..:|:::|.||.||..
  Rat   647 ARDEFEGLFKQSAENVNQYLMDPKFMERTLQLAGTQPLEVLEAIQCSLVLQRPQTWADCVTWAYQ 711

  Fly   848 YWEDQYVNQIKQLLFNFPPDQITSSGQPFWSGPKRCPDPLVFDVNDPMHLDFIYAAANLRAEVYG 912
            :|..||.:.|:|||.||||||:||||..|||||||||.||.||.|:|:|||::.|||||.|:.||
  Rat   712 HWHTQYSHNIQQLLHNFPPDQLTSSGVLFWSGPKRCPHPLTFDTNNPLHLDYVMAAANLFAQTYG 776

  Fly   913 IEQVRNRETIAELVQKVKVPEFKPRSGVKIETNEAAAAASANNFDDGELDQDRVDKIISELLKNA 977
            :|..::...:..|:|.:..|:|.|:||::|..:|....:::...||..|::      :...|...
  Rat   777 LEGSQDCAAVTTLLQSLPAPKFAPKSGIRIHVSEQELQSTSATVDDSHLEE------LKTSLPTP 835

  Fly   978 DK--SSKITPLEFEKDDDSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIATTTSVL 1040
            ||  ..|:.|::||||||||.|||||||.|||||.||.|||||||||||||||||||||||||.:
  Rat   836 DKMLGFKMHPIDFEKDDDSNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTSAV 900

  Fly  1041 SGLAVLEVIKLIVGHRDLVKFKNGFANLALPFMAFSEPLPAAKNTYYGKEWTLWDRFEVTG---- 1101
            .||..||:.|::.||:.|..|||.|.||||||.:||.||....:.||.|:|||||||:|.|
  Rat   901 VGLVCLELYKVVQGHQQLDSFKNSFINLALPFFSFSAPLAPGYHQYYDKKWTLWDRFDVQGLQPS 965

  Fly  1102 --ELSLQEFLNYFEENEKLKITMLSQGVSMLYSFFMPKAKCSERLPLPMSEVVRRVSKRRLEPHE 1164
              |::|::||:||:...||:||:||||||||||||||..|..|||..||:|:|.|||||:|..|.
  Rat   966 GEEMTLKQFLDYFKTEHKLEITILSQGVSMLYSFFMPATKLQERLDQPMTEIVSRVSKRKLGQHV 1030

  Fly  1165 RSLVFEICCNDVDGEDVEVPYVRYTL 1190
            :|||||:|||:..|:|:|||||||.:
  Rat  1031 KSLVFELCCNNESGDDIEVPYVRYII 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	595/1013 (59%)
Uba1y	NP_001395667.1	Ube1	48..1054	CDD:273603	595/1013 (59%)