Protein Alignment Uba1 and Uba1y

DIOPT Version :10

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_030107423.1
• Gene: Uba1y / 22202
• MGIID: 98891
• Length: 1087
• Species: Mus musculus
• Alignment Length: 1072
• Identity: 589/1072 - (54%)
• Similarity: 758/1072 - (70%)
• Gaps: 73/1072 - (6%)

  Fly   169 SNNSTNNRQLEGSSNMAGNSAAAGGDIDESLYSRQLYVLGHDAMRRMANSDILLSGLGGLGLEIA 233
            :|..:.|:::               ||||||||||||||||:||:.:..|.:|:|||.|||:|||
Mouse    38 TNEMSKNKEM---------------DIDESLYSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIA 87

  Fly   234 KNVILGGVKSITLHDTATCGLHDLSSQFYLTEADIGKNRAEASCAQLAELNNYVRTVSHTGPLTE 298
            ||:||||||::||||.......||||||.|.|.||||||||.|..:|||||:||...::||||.|
Mouse    88 KNIILGGVKAVTLHDQGIAQWADLSSQFCLREEDIGKNRAEISQPRLAELNSYVPVFAYTGPLIE 152

  Fly   299 EFLRKFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETRGLFAKVFCDFGESFTIYDQDGTQPIS 363
            |||..|:||||||:..|.|.::.:|.|.:||.|::|:||||..::||||||...:.|.:|.||:|
Mouse   153 EFLSGFQVVVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLS 217

  Fly   364 TMIASITHDAQGVVTCLDETRHGFNDGDYVTFSEVQGMQELNGCQPLKITVLGPYTFSIGDTSKF 428
            .|::.||.:..|:||||:::||||..||:::|:|||||.||||..|::|.|||||||||.|||.|
Mouse   218 AMVSMITKENPGIVTCLEDSRHGFESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFSICDTSSF 282

  Fly   429 GEYKSGGVATQVKMPKTISFKPLAQATEEPEFLISDFAKLDSPATLHVAFNALSCYRKAHNGALP 493
            .||..||:.:|||:|:.|:||||..:..||||:::||||...||.||:.|.||..:...|:.. |
Mouse   283 SEYIRGGIVSQVKVPRKINFKPLLASLAEPEFVVTDFAKCCHPAQLHIGFQALHQFCTQHSRP-P 346

  Fly   494 RPWNEEDANSFLEVVRASSNAE---------VDEKLVLQFAKICSGNTCPLDAAVGGIVAQEVLK 549
            ||.|||||...:.:.: |.||:         :|..|:.:.|.:.:|:..|::|..||:.||||:|
Mouse   347 RPHNEEDAEELVTLAQ-SVNAQALPAVQQDCLDIDLIRKLAYVAAGDLAPMNAFFGGLAAQEVMK 410

  Fly   550 ACSGKFTPIYQWLYFDALECLPTEGVE--EADAQPVGSRYDSQIAIFGKKFQEKLADSKWFIVGA 612
            ||||||.||.||||||||||||...|.  |....|..:|||.|:|:||...||||...|:|:|||
Mouse   411 ACSGKFMPIRQWLYFDALECLPEHRVAFMEDKCLPHQNRYDGQVAVFGSDLQEKLGKQKYFLVGA 475

  Fly   613 GAIGCELLKNFGMLGLGTG-NGQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNP 676
            |||||||||||.|:|||.| :|:|.|||||.||||||||||||||.|:.|.||.|||.|::.:||
Mouse   476 GAIGCELLKNFAMIGLGCGEDGEITVTDMDTIEKSNLNRQFLFRPWDITKLKSETAAAAVRDINP 540

  Fly   677 EVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGN 741
            .:.:.:::.|||.|||.|:.:|||.|||||||||||||||:|:||:|::.|.||:|:|||||.||
Mouse   541 HIRIFSHQNRVGPETEHVYDDDFFQKLDGVANALDNVDARLYVDRRCVYYRKPLLESGTLGTKGN 605

  Fly   742 VQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQ------------------------- 781
            |||:|||.||||||||||||||||||||||||||||||:|
Mouse   606 VQVVVPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTVQGRLHALKKVARWTSGFFLCTSVLVL 670

  Fly   782 ----WARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPLEILDSIKKALIDDKPKSFAHCV 842
                ||||.|||:|||||||..||:.||:|.||..:|.|.||||:|::|..:|:..:|:::|.||
Mouse   671 LVLPWARDEFEGLFKQSAENVNQYLTDPKFMERTLQLAGTQPLEVLEAIHCSLVLQRPQTWADCV 735

  Fly   843 EWARLYWEDQYVNQIKQLLFNFPPDQITSSGQPFWSGPKRCPDPLVFDVNDPMHLDFIYAAANLR 907
            .||..:|..||.:.|:|||.||||.|:||||..|||||||||.||.||:|:|:|||::.|||||.
Mouse   736 TWAYQHWHTQYSHNIQQLLHNFPPAQLTSSGALFWSGPKRCPHPLTFDINNPLHLDYVMAAANLF 800

  Fly   908 AEVYGIEQVRNRETIAELVQKVKVPEFKPRSGVKIETNE-AAAAASANNFDDGELDQDRVDKIIS 971
            |:.||:...::...:|:|:|.:.||:|.|:||::|..:| ...:.||...||..|::      :.
Mouse   801 AQTYGLGGSQDCAVVAKLLQSLPVPKFAPKSGIRIHVSEQELQSTSATTIDDSHLEE------LK 859

  Fly   972 ELLKNADK--SSKITPLEFEKDDDSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIA 1034
            ..|...||  ..|:.|::||||||||.|||||||.|||||.||.|.|||||||||||||||||||
Mouse   860 TALPTPDKLLGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYGISPADRHKSKLIAGKIIPAIA 924

  Fly  1035 TTTSVLSGLAVLEVIKLIVGHRDLVKFKNGFANLALPFMAFSEPLPAAKNTYYGKEWTLWDRFEV 1099
            ||||.:.||..||:.|::.||:.|..:||.|.|||||..:||.||....:.||.:||||||||:|
Mouse   925 TTTSAIVGLVCLELYKVVQGHQQLESYKNSFINLALPLFSFSAPLAPECHQYYDQEWTLWDRFDV 989

  Fly  1100 TG------ELSLQEFLNYFEENEKLKITMLSQGVSMLYSFFMPKAKCSERLPLPMSEVVRRVSKR 1158
            .|      |::|::||:||:...||::.|||||||||||.|||.:|..|||..||:|:|..|||:
Mouse   990 QGLQPSGEEMTLKQFLDYFKTEHKLEVIMLSQGVSMLYSVFMPASKLKERLDQPMTEIVSCVSKQ 1054

  Fly  1159 RLEPHERSLVFEICCNDVDGEDVEVPYVRYTL 1190
            :|..|.:|||||:|||...|:|:|||||||.:
Mouse  1055 KLGHHVKSLVFELCCNSDSGDDIEVPYVRYII 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	585/1043 (56%)
Uba1y	XP_030107423.1	Ube1	48..1084	CDD:273603	585/1043 (56%)