DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba1 and moc-3

DIOPT Version :9

Sequence 1:	NP_477310.2	Gene:	Uba1 / 35998	FlyBaseID:	FBgn0023143	Length:	1191	Species:	Drosophila melanogaster
Sequence 2:	NP_501359.1	Gene:	moc-3 / 177607	WormBaseID:	WBGene00018357	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	61/217 - (28%)
Similarity:	89/217 - (41%)	Gaps:	38/217 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   560 QWLYFDALECLPTEGVEEADAQPVGSRYDSQIAI--FGKKFQEKLADSKWFIVGAGAIGCELLKN 622
            ||:          .|:.:.||    .||..|:.:  ||...|:.|.:....|||||.:||.:...
Worm     5 QWV----------AGISKKDA----GRYSRQLLVDDFGVSGQKNLKNLNVLIVGAGGLGCPVATY 55

  Fly   623 FGMLGLGTGNGQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRV 687
            .|..|:||    |.:.|.|.|...||:||..::...|.|.|:...||.||..|.::||..:...:
Worm    56 LGAAGIGT----IGIVDYDHISLDNLHRQVAYKEDQVGKSKAQALADNIKLQNSDLNVQVHNTSL 116

  Fly   688 GAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATES 752
            .:..    :...|...:.|.:..|||..|..::..|:...||||....|...|.:.|
Worm   117 DSSN----AMQLFKNYEIVCDCTDNVATRYLINDVCVLLNIPLVSGSALRWDGQLSV-------- 169

  Fly   753 YSSSQDPPEKSIPICTLKNFPN 774
            |....|.|      |....||:
Worm   170 YHYGSDCP------CYRCLFPS 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	61/217 (28%)
		Ube1_repeat1	199..574	CDD:238768	2/13 (15%)
		E1_4HB	447..510	CDD:292809
		Ube1_repeat2	606..1144	CDD:238767	49/169 (29%)
moc-3	NP_501359.1	PRK07878	8..402	CDD:181156	59/204 (29%)
		ThiF_MoeB_HesA_family	17..246	CDD:238386	56/191 (29%)
		RHOD_ThiF	283..402	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810