DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Uba1 and ATG7

DIOPT Version :9

Sequence 1:	NP_477310.2	Gene:	Uba1 / 35998	FlyBaseID:	FBgn0023143	Length:	1191	Species:	Drosophila melanogaster
Sequence 2:	XP_006712994.1	Gene:	ATG7 / 10533	HGNCID:	16935	Length:	738	Species:	Homo sapiens

Alignment Length:	91	Identity:	27/91 - (29%)
Similarity:	45/91 - (49%)	Gaps:	7/91 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   600 EKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNRQFLFRPHDV---QK 661
            :|:...|..::|||.:||.:.:..    :|.|...|...|...|..||..||.|:...|.   .|
Human   351 DKVVSVKCLLLGAGTLGCNVARTL----MGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGK 411

  Fly   662 PKSMTAADAIKRMNPEVNVTAYELRV 687
            ||::.|||.::::.|.||...:.:.:
Human   412 PKALAAADRLQKIFPGVNARGFNMSI 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	27/91 (30%)
		Ube1_repeat1	199..574	CDD:238768
		E1_4HB	447..510	CDD:292809
		Ube1_repeat2	606..1144	CDD:238767	26/85 (31%)
ATG7	XP_006712994.1	ATG7_N	13..321	CDD:293029
		E1_like_apg7	15..693	CDD:273590	27/91 (30%)
		Apg7	357..682	CDD:238763	26/85 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900