Protein Alignment Uba1 and uba1

DIOPT Version :10

• Sequence 1: NP_477310.2
• Gene: Uba1 / 35998
• FlyBaseID: FBgn0023143
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_031747323.1
• Gene: uba1 / 100495145
• -ID: -
• Length: 1059
• Species: Xenopus tropicalis
• Alignment Length: 1069
• Identity: 636/1069 - (59%)
• Similarity: 785/1069 - (73%)
• Gaps: 40/1069 - (3%)

  Fly   145 SQEASSSASATSNSNNNVSSSNNNSNNSTNNRQLEGSSNMA--GNSAAAGGDIDESLYSRQLYVL 207
            |::...|.|.|.      :.||.:|:||.:..|...::.||  ||||    :|||.|||||||||
 Frog     7 SKKRRVSGSETK------TGSNCSSSNSVSTDQTAPANGMARNGNSA----EIDEGLYSRQLYVL 61

  Fly   208 GHDAMRRMANSDILLSGLGGLGLEIAKNVILGGVKSITLHDTATCGLHDLSSQFYLTEADIGKNR 272
            |||||:||.||::|:||:.|||:|||||:|||||||:|:||.......||||||||.|.|:||||
 Frog    62 GHDAMKRMQNSNVLISGMSGLGVEIAKNIILGGVKSVTIHDQGNTEWADLSSQFYLREGDVGKNR 126

  Fly   273 AEASCAQLAELNNYVRTVSHTGPLTEEFLRKFRVVVLTNSDGEEQQRIAKFAHENGIALIIAETR 337
            ||.|..:|||||.||...|.||||||:||..|::|:||.:..|||.|:..|.|.:.|..|:|:||
 Frog   127 AEVSHPRLAELNTYVPVSSSTGPLTEDFLSAFQLVILTAATMEEQLRVGDFCHSHDIKFIVADTR 191

  Fly   338 GLFAKVFCDFGESFTIYDQDGTQPISTMIASITHDAQGVVTCLDETRHGFNDGDYVTFSEVQGMQ 402
            |||.::|||||:...:.|.:|.||:|.||:.||.|..||||||||.||||..||:|||:||:||.
 Frog   192 GLFGQLFCDFGKEMVVMDPNGEQPLSAMISMITKDNPGVVTCLDEARHGFETGDFVTFTEVRGMT 256

  Fly   403 ELNGCQPLKITVLGPYTFSIGDTSKFGEYKSGGVATQVKMPKTISFKPLAQATEEPEFLISDFAK 467
            |||||:|::|.|||||||||.|||:|.:|..||:..||||||.||||||.::.:||:||::||||
 Frog   257 ELNGCEPVEIKVLGPYTFSICDTSRFSDYVRGGIVAQVKMPKKISFKPLRESLQEPDFLVTDFAK 321

  Fly   468 LDSPATLHVAFNALSCYRKAHNGALPRPWNEEDANSFLEVVR--------ASSNAEVDEKLVLQF 524
            .|.||.||:.|..|..:||.| |.||:..||.||...|.:.:        |....||.|.|:.|.
 Frog   322 FDHPAQLHLGFQGLHEFRKKH-GHLPKAHNEADAQEVLALTQTLNEGAPGAVKQEEVKESLIKQL 385

  Fly   525 AKICSGNTCPLDAAVGGIVAQEVLKACSGKFTPIYQWLYFDALECLPTEGVE----EADAQPVGS 585
            |....||..|::|.:||:.|||.:|||||||.||.||||||||||||.|..:    |.:..|..|
 Frog   386 AYQARGNLAPINAFIGGLAAQEAMKACSGKFMPIMQWLYFDALECLPEENADATLTEENCSPKNS 450

  Fly   586 RYDSQIAIFGKKFQEKLADSKWFIVGAGAIGCELLKNFGMLGLGTG-NGQIFVTDMDLIEKSNLN 649
            |||.|||:||..|||:|...|:|:||||||||||||||.|:||..| .|:|.|||||.|||||||
 Frog   451 RYDGQIAVFGSTFQEQLGKQKYFLVGAGAIGCELLKNFAMIGLAAGEGGEITVTDMDTIEKSNLN 515

  Fly   650 RQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVD 714
            |||||||.||.|.||.|||.|:|:|||.:.|||::.|||.|||||:.:|||..||||||||||:|
 Frog   516 RQFLFRPWDVTKMKSETAAAAVKQMNPNLRVTAHQNRVGTETEKVYDDDFFEALDGVANALDNID 580

  Fly   715 ARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHT 779
            ||:||||:|::.|.||:|:|||||.|||||::||.||||||||||||||||||||||||||||||
 Frog   581 ARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHT 645

  Fly   780 LQWARDAFEGVFKQSAENAAQYIADPQFTERIAKLPGIQPLEILDSIKKALIDDKPKSFAHCVEW 844
            ||||||.|||:|||.|||..||:.||:|.||..||||.||||:::::.|:|:.::|||:|.||.|
 Frog   646 LQWARDEFEGLFKQPAENVNQYLTDPKFMERTLKLPGSQPLEVVEAVYKSLVTERPKSWADCVTW 710

  Fly   845 ARLYWEDQYVNQIKQLLFNFPPDQITSSGQPFWSGPKRCPDPLVFDVNDPMHLDFIYAAANLRAE 909
            |..:|..||.|.|:|||.||||||:||:|.||||||||||.||.|..:..:|:|:|.|||||.|.
 Frog   711 ACKHWHIQYSNNIRQLLHNFPPDQLTSAGVPFWSGPKRCPHPLTFSGSTGLHVDYIMAAANLFAL 775

  Fly   910 VYGIEQVRNRETIAELVQKVKVPEFKPRSGVKIETNEAAAAASANNFDDGELDQDRVDKIISELL 974
            .|||...::|..:.|:::.||||||.|:|||||..::.....:..:.||..|::      :...|
 Frog   776 SYGIGGSKDRGAVVEILRGVKVPEFTPKSGVKIHVSDQEIQNAHASLDDTRLEE------LKHTL 834

  Fly   975 KNADK--SSKITPLEFEKDDDSNLHMDFIVACSNLRAANYKIPPADRHKSKLIAGKIIPAIATTT 1037
            ...:.  |.|:.|::||||||:|.|||||||.|||||.||.||||||||||||||||||||||||
 Frog   835 PTPESLASFKMFPIDFEKDDDTNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTT 899

  Fly  1038 SVLSGLAVLEVIKLIVGHRDLVKFKNGFANLALPFMAFSEPLPAAKNTYYGKEWTLWDRFEVTG- 1101
            ..:.||..||:.|:|.|||.|..|||||.||||||..||||:.|.|:.||..||||||||||.|
 Frog   900 GAVVGLVCLELYKIIQGHRKLESFKNGFMNLALPFFGFSEPIAAPKHKYYDNEWTLWDRFEVKGV 964

  Fly  1102 -----ELSLQEFLNYFEENEKLKITMLSQGVSMLYSFFMPKAKCSERLPLPMSEVVRRVSKRRLE 1161
                 |::|::||:||:|..||:|||||||||||||||||.||..|||..||:::|.:|||:::.
 Frog   965 QSNGDEMTLKQFLDYFKEEHKLEITMLSQGVSMLYSFFMPAAKLKERLEQPMTDIVTKVSKKKIG 1029

  Fly  1162 PHERSLVFEICCNDVDGEDVEVPYVRYTL 1190
            .|.::||||:||||...|||||||||||:
 Frog  1030 KHVKALVFELCCNDESDEDVEVPYVRYTI 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba1	NP_477310.2	Ube1	194..1188	CDD:273603	617/1014 (61%)
uba1	XP_031747323.1	Ube1	48..1056	CDD:273603	617/1014 (61%)