DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mmp2 and AT1G24140

DIOPT Version :9

Sequence 1:	NP_995788.1	Gene:	Mmp2 / 35997	FlyBaseID:	FBgn0033438	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_173824.2	Gene:	AT1G24140 / 839026	AraportID:	AT1G24140	Length:	384	Species:	Arabidopsis thaliana

Alignment Length:	297	Identity:	92/297 - (30%)
Similarity:	137/297 - (46%)	Gaps:	34/297 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 IMYNYLMQFDYLPKSDLETGALRT--EDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVG 111
            ::..|...|.|:.:::| :|....  :|.||.|:...|....:.|||.:|..|.:.:..||||
plant    63 MLKQYFQHFGYITETNL-SGNFTDDFDDILKNAVEMYQRNFQLNVTGVLDELTLKHVVIPRCG-- 124

  Fly   112 DRRSADSFSPDNLYH------EIGSNVRVRRF-ALQ-------GPKW--SRTDLTWSMVNRSMPD 160
               :.|..:..:..|      |:....|.:|| |::       .|:|  :|.|||::...|:..
plant   125 ---NPDVVNGTSTMHSGRKTFEVSFAGRGQRFHAVKHYSFFPGEPRWPRNRRDLTYAFDPRNAL- 185

  Fly   161 ASKVERMVQTALDVWANHSKLTFREVYS-DQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEG 224
            ..:|:.:...|...|...:.|||..|.. ..:||.|.|....||||..||||.:.|||||.|..|
plant   186 TEEVKSVFSRAFTRWEEVTPLTFTRVERFSTSDISIGFYSGEHGDGEPFDGPMRTLAHAFSPPTG 250

  Fly   225 RGGDAHFDADETWNFDGESDD-----SHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEV 284
            .   .|.|.:|.|...||..|     |...:..:||:||:||.|||.||::..::|:|..:....
plant   251 H---FHLDGEENWIVSGEGGDGFISVSEAVDLESVAVHEIGHLLGLGHSSVEGSIMYPTIRTGRR 312

  Fly   285 AGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTT 321
            ..:|..||..|:|.|||......|...|..:|....|
plant   313 KVDLTTDDVEGVQYLYGANPNFNGSRSPPPSTQQRDT 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	59/165 (36%)
		ZnMc_MMP	143..301	CDD:239805	59/165 (36%)
		HX	513..707	CDD:238046
AT1G24140	NP_173824.2	PG_binding_1	64..116	CDD:279773	15/52 (29%)
		Peptidase_M10	167..329	CDD:278824	59/165 (36%)
		ZnMc_MMP	167..329	CDD:239805	59/165 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I2423
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm995
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920