Protein Alignment Mmp2 and mmp30

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001035381.1
• Gene: mmp30 / 678531
• ZFINID: ZDB-GENE-060421-5765
• Length: 475
• Species: Danio rerio
• Alignment Length: 717
• Identity: 170/717 - (23%)
• Similarity: 262/717 - (36%)
• Gaps: 265/717 - (36%)

  Fly     8 ATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISED--IMYNYLMQFDYLPKSDLETGAL 70
            |.|:.:.:.::|        .|:.:|         |..:||  |...||.|| |......:|...
Zfish     6 AALILVVSLTLC--------NGAPTT---------TPSTEDREIAEAYLSQF-YRDSKAAKTLGR 52

  Fly    71 RTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVR 135
            .....|:..::::|||..:.|||::||.|.:.::.|||||.|                     |.
Zfish    53 MFVSNLENELKAMQSFFGLEVTGQLDSNTLKTMKLPRCGVTD---------------------VA 96

  Fly   136 RFA-LQG-PKWSRTDLTWSMVN-RSMPDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILF 197
            ||. .:| |:|.::.:|:.:.. .:.....:|:..:..|..::::...:.|::::|..|||.|||
Zfish    97 RFGHFEGKPRWKQSVVTYRITEYTTQLSQREVDSTIAKAFQLYSDVIPVDFKQIFSGTADIMILF 161

  Fly   198 ARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHS 262
            ....|||.|.||||..|||||..||..:|||.|||.||.|:.     .||..|.|.||.||.||:
Zfish   162 KGGDHGDFYPFDGPNGVLAHANSPGPEQGGDTHFDDDEKWSL-----SSHNINLLLVAAHEFGHA 221

  Fly   263 LGLAHSAIPDAVMFPWYQN-NEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRA 326
            |||.||....|:|:|.|:. :..|..||.|||.|:|.|||.:..|
Zfish   222 LGLDHSRDSSALMYPTYRYVSTNAYTLPRDDRLGVQALYGVRAST-------------------- 266

  Fly   327 MIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQR 391
                                                                             
Zfish   267 ----------------------------------------------------------------- 266

  Fly   392 QEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDR 456
                                                |:|.
Zfish   267 ------------------------------------NKPE------------------------- 270

  Fly   457 RRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCM--TY 519
                                           |:|..||.|          :|....|:.|.  ..
Zfish   271 -------------------------------PKPEPKPNP----------QPAPSPPEPCKRDLI 294

  Fly   520 YDAISIIRGELFIFRGPYLWRIGTSGLYNGYP-TEIRRHWSALPENLTKVDAVYENKQRQIVF-F 582
            :||.:.|||||:.|:..|.|:   .|.|:|.. .||:..|    .::..|||.||.:.:...| |
Zfish   295 FDAATRIRGELYFFKDRYYWK---KGYYSGLTLLEIKTTW----PSIDSVDAAYEFQDKGTNFLF 352

  Fly   583 IGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVEL 647
            .|::::......:..|:|||:::.|.|.::..|||:.......||....|:.||..:|.|.:::.
Zfish   353 KGQQFWAVKGNTILSGYPKPISTYGFPSSVNKIDAAVHVKSTGRTLFFVGSKYWSFNDRTSKMDR 417

  Fly   648 DYPRDMSI-WSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARR------WM 705
            .:|:.:|. :.|:|..:||||:          |.||..|:|...:..:..|.....|      |:
Zfish   418 GFPKSISADFPGIGSKVDAAFE----------NYGYLYFSDGARQTEYIFASRRVNRVLLNYGWL 472

  Fly   706 QC 707
            .|
Zfish   473 DC 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	16/50 (32%)
		Peptidase_M10	143..301	CDD:425668	64/159 (40%)
		HX	513..707	CDD:238046	58/204 (28%)
mmp30	NP_001035381.1	PG_binding_1	26..85	CDD:460223	19/59 (32%)
		Peptidase_M10	106..261	CDD:425668	64/159 (40%)
		HX	293..474	CDD:238046	56/197 (28%)