Protein Alignment Mmp2 and mmp11a

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_021334138.1
• Gene: mmp11a / 563753
• ZFINID: ZDB-GENE-070817-3
• Length: 483
• Species: Danio rerio
• Alignment Length: 605
• Identity: 172/605 - (28%)
• Similarity: 224/605 - (37%)
• Gaps: 230/605 - (38%)

  Fly    99 TARLIQKPRCGVGDRRSADSFSPDNLYHEIGS-NVRVRRFALQGPKWSRTDLT-------WSMVN 155
            ::|.....||||.|            |.|... ::|.:|:.|.|.:|.:||||       |.|
Zfish    80 SSRATGPKRCGVPD------------YPEQRDVHLRQKRYVLFGGRWPKTDLTYKIQRFPWQM-- 130

  Fly   156 RSMPDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFY 220
                ...||.|:.|.||.||::.:.|||.||.:.:|||.|.|.|..|||...|||||.:|||||:
Zfish   131 ----REDKVRRIFQEALKVWSDVTPLTFTEVVNQEADIVIDFTRYWHGDNLPFDGPGGILAHAFF 191

  Fly   221 PGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVA 285
            |...|.||.|||.||:|....|.    ||:.|.||.||.||.|||.||.:|.|:|.|:|..:...
Zfish   192 PRTHREGDIHFDYDESWTVGNEL----GTDLLQVAAHEFGHVLGLQHSLVPGAIMSPFYSFSYPL 252

  Fly   286 GNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDR 350
             .|.:||:.|||.|||...:.    :||....|.            |.|:.:|
Zfish   253 -KLSEDDKKGIQYLYGPPVRA----QPQIPAETN------------DIPSAFP------------ 288

  Fly   351 NRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEH 415
                                                                             
Zfish   289 ----------------------------------------------------------------- 288

  Fly   416 KSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPV 480
                                                                             
Zfish   289 ----------------------------------------------------------------- 288

  Fly   481 TPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSG 545
                                            ||:|.|.:||:||||||||.|:..|.|||....
Zfish   289 --------------------------------PDACHTDFDAVSIIRGELFFFKASYAWRIRDGR 321

  Fly   546 LYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPP 610
            |..|||....||||.:|:   |:||.||:|:..|.||.|..|:||::.....| |..|.||||
Zfish   322 LQAGYPALASRHWSGIPQ---KIDAAYEDKKGNIWFFEGSNYWVFDAEHRIKG-PDSLLSLGL-- 380

  Fly   611 TLTHIDASF--VWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDM-SIWSGVGYNIDAAFQYLDG 672
            .:::|.|:.  ...|:..||......|||:|....:|:...||.: ..|.||...||||||...|
Zfish   381 RVSNIQAALRVKEHHSQHTYFFKSGNYWRLDPQENRVDTSAPRRIQQDWWGVPEEIDAAFQEASG 445

  Fly   673 KTYFFKNLGYWEFNDDRMKV 692
            ...|.....||:|:..:.||
Zfish   446 FVVFISRRQYWKFDPVQRKV 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	1/3 (33%)
		Peptidase_M10	143..301	CDD:425668	76/164 (46%)
		HX	513..707	CDD:238046	76/183 (42%)
mmp11a	XP_021334138.1	ZnMc_MMP	113..267	CDD:239805	76/164 (46%)
		HX	289..480	CDD:238046	76/183 (42%)