Protein Alignment Mmp2 and mmp9

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001006843.1
• Gene: mmp9 / 448591
• XenbaseID: XB-GENE-876295
• Length: 670
• Species: Xenopus tropicalis
• Alignment Length: 852
• Identity: 168/852 - (19%)
• Similarity: 258/852 - (30%)
• Gaps: 389/852 - (45%)

  Fly    10 LLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISE-DIMYNYLMQFDYLPKSDLETGALRTE 73
            :||:.| .:|.:..|:|.......:.|...:.:::::. ::...||:||.|:.:   |.|:..|
 Frog     6 VLAIVA-ILCSRGHSVPTNSKTPLSITFPGEIQSSMTNAELAERYLLQFGYMTQ---EQGSNVT- 65

  Fly    74 DQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFA 138
              ||.|:..:|....:|.||.:|:.|...:::||||..|....::|..|
 Frog    66 --LKNALTLMQQKLGLTRTGVLDTETLEAMRRPRCGFPDIGKFNTFDGD---------------- 112

  Fly   139 LQGPKWSRTDLTWSMVNRSMPDASK--VERMVQTALDVWANHSKLTFREVYSDQADIQILFARRA 201
               .||...|:|:.:::.| ||...  ::.....|..||::.:.|||..:||.:.||.|||....
 Frog   113 ---LKWDHNDITYRILSYS-PDLDPEVIDDAFARAFKVWSDVTPLTFTRIYSGEPDINILFGPED 173

  Fly   202 HGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWN------------------------FDGE 242
            |||.|.|||...:||||:.||.|..||||||.||.|.                        |||:
 Frog   174 HGDPYPFDGKDGLLAHAYPPGPGVQGDAHFDEDEFWTLGTGTVVKTRFGNAEGALCHFPFIFDGQ 238

  Fly   243 S---------------------------------------------------------------- 243
            |
 Frog   239 SYSSCTTSGRSDGLPWCSTTPSYDQDKKYGFCPSELLYTYGGNSEGQPCVFPFIFDGVSYNGCTK 303

  Fly   244 -------------------------------------------------------------DD-- 245
                                                                         ||
 Frog   304 EGRQDGYRWCSTTADYDQDQKYGFCPNRDTAVIGGNSQGEPCVFPFTFQGKRFNSCTTDGRDDRK 368

  Fly   246 -------------------SHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDD 291
                               ..|.:...||.||.||:|||.||.:.||:|:|.|...: ...|.:|
 Frog   369 LWCATTSSYDQDRKWGFCPDQGYSLFLVAAHEFGHALGLEHSEVQDALMYPMYSYVK-DFQLHED 432

  Fly   292 DRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARER 356
            |..|||.||||                            ..:|          ||
 Frog   433 DVRGIQYLYGT----------------------------GSRP----------NP---------- 449

  Fly   357 QEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWER 421
                                                                             
 Frog   450 ----------------------------------------------------------------- 449

  Fly   422 NPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANT 486
            ||.|...:|...:...|                                               |
 Frog   450 NPPKSTKKPLATKSPRR-----------------------------------------------T 467

  Fly   487 TPRPTNKPYPTVHRQHHHHNKPRKPKPDSC-MTYYDAISIIRGELFIFRGPYLWRIGTSGLYNG- 549
            |.||.               :|..|..|:| :..:|||:.::|.|..|:....|.: |....|.
 Frog   468 TTRPV---------------RPVDPAQDACKVEKFDAIADLQGALHFFKDGLYWTL-TPRSKNAP 516

  Fly   550 -YPTEIRRHWSALPENLTKVDAVYEN-KQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTL 612
             .|..|...|..||   :::|..::: ..:.|.||.|.:::.:.:.. |.| |:.:..|||...:
 Frog   517 QNPQRISDTWPGLP---SRIDTAFQDPTSKSIFFFSGLKFWQYTATS-ALG-PRSIEKLGLNKDV 576

  Fly   613 THIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMSI-WSGVGYNIDAAFQYLDGKTYF 676
            ..|..||. ..|.:..:.:|..|||::..|..::..|||..:. :.||..:....|.| .|..||
 Frog   577 ESIMGSFA-RDNGKALLFNGERYWRLNLKTLTIDNGYPRQTAADYPGVPGDSHDVFLY-QGNYYF 639

  Fly   677 FKNLGYW 683
            .::..:|
 Frog   640 CQDQYFW 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	17/50 (34%)
		Peptidase_M10	143..301	CDD:425668	73/329 (22%)
		HX	513..707	CDD:238046	47/176 (27%)
mmp9	NP_001006843.1	PG_binding_1	39..93	CDD:460223	17/59 (29%)
		Peptidase_M10	114..442	CDD:425668	73/329 (22%)
		FN2	222..270	CDD:128373	4/47 (9%)
		FN2	280..328	CDD:128373	0/47 (0%)
		FN2	338..386	CDD:128373	2/47 (4%)
		HX	480..667	CDD:238046	47/175 (27%)