| Sequence 1: | NP_995788.1 | Gene: | Mmp2 / 35997 | FlyBaseID: | FBgn0033438 | Length: | 758 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004521.1 | Gene: | MMP2 / 4313 | HGNCID: | 7166 | Length: | 660 | Species: | Homo sapiens |
| Alignment Length: | 779 | Identity: | 186/779 - (23%) |
|---|---|---|---|
| Similarity: | 291/779 - (37%) | Gaps: | 220/779 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 16 QSMCIQELSLPPEGSHSTAATR-------SKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTE 73
Fly 74 DQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFA 138
Fly 139 LQGPKWSRTDLTWSMVNRSMP-DASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAH 202
Fly 203 GDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETW-------------NFDGESDD----SHGTN 250
Fly 251 FLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGI---QQLYGTKEKTWG---- 308
Fly 309 -PYKPQTTTTTTTTTTMRAMIYR---------ADK--------------------PAYWPWNNPS 343
Fly 344 NNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQER----- 403
Fly 404 ---QEEENRRRKIEHKSQ----------WERNPSKERNRPRERQEMERRRQEQERQEQERQEQED 455
Fly 456 RRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCM--T 518
Fly 519 YYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQ-IVFF 582
Fly 583 IGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVEL 647
Fly 648 DYPRDMS-IWSGVGYNIDAAFQYL-DGKTYFFKNLGYWEFNDDRMKVAHARAKLSARR--WMQC 707 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mmp2 | NP_995788.1 | Peptidase_M10 | 143..301 | CDD:278824 | 56/178 (31%) |
| ZnMc_MMP | 143..301 | CDD:239805 | 56/178 (31%) | ||
| HX | 513..707 | CDD:238046 | 67/200 (34%) | ||
| MMP2 | NP_004521.1 | PG_binding_1 | <70..97 | CDD:307564 | 8/26 (31%) |
| Cysteine switch. /evidence=ECO:0000250 | 100..107 | 6/25 (24%) | |||
| Collagenase-like 1 | 110..221 | 43/110 (39%) | |||
| Peptidase_M10 | 118..446 | CDD:306839 | 80/404 (20%) | ||
| Collagen-binding | 222..396 | 31/213 (15%) | |||
| FN2 | 226..274 | CDD:128373 | 14/63 (22%) | ||
| FN2 | 284..332 | CDD:128373 | 11/47 (23%) | ||
| FN2 | 342..390 | CDD:128373 | 5/71 (7%) | ||
| Collagenase-like 2 | 397..465 | 15/122 (12%) | |||
| Required for inhibitor TIMP2 binding. /evidence=ECO:0000269|PubMed:1655733 | 414..660 | 79/307 (26%) | |||
| HX | 466..660 | CDD:238046 | 67/200 (34%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1565 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1075463at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR10201 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X44 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.920 | |||||