Protein Alignment Mmp2 and LOC3290935

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_061502994.1
• Gene: LOC3290935 / 3290935
• VectorBaseID: AGAMI1_003964
• Length: 582
• Species: Anopheles gambiae
• Alignment Length: 706
• Identity: 213/706 - (30%)
• Similarity: 309/706 - (43%)
• Gaps: 154/706 - (21%)

  Fly    18 MCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRS 82
            :|:..|.|    .|...|..:|:         |.:::.:|.||.|...:..||.:.:.:.:||:.
Mosquito    14 LCLISLRL----MHGAPAVPTKE---------MIDFMRRFGYLEKGPTQAEALYSGEAIIDAIKH 65

  Fly    83 LQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRT 147
            :|.||.:..||.:|..|..|:..|||||.|....|            .::|.||:.:....|.:.
Mosquito    66 VQKFGALPQTGVLDRRTIELMSAPRCGVVDVMQHD------------QSLRHRRYVIGSESWRKR 118

  Fly   148 DLTWSMVNRSM---PDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFD 209
            .:|:.:.|.|.   .||  |.:.:..|...|:.:|||.|..||...|||.:.|....|||.|.||
Mosquito   119 RITYFIANWSSKVGEDA--VAKFMAKAFGEWSKYSKLRFVRVYDPSADIIVGFGSGHHGDNYPFD 181

  Fly   210 GPGQVLAHAFYPGE--GRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPD 272
            |||.||||||||.|  ..|||.|||.||.|. :..:..|.|.:|.:||:||||||||||||.:..
Mosquito   182 GPGNVLAHAFYPYEMNAYGGDVHFDEDENWK-ENSTHLSEGVDFYSVAIHELGHSLGLAHSPVYS 245

  Fly   273 AVMFPWYQNNEVA-GNLPDDDRYGIQQLY-----GTKEKTWGPYKPQTTTTTTTTTTMRAMIYR- 330
            ::|||:|:.  :| |.|..||...:.|||     .|.|..| .|..:.:||.....|:...:.|
Mosquito   246 SLMFPYYKG--IAQGTLDYDDILAMYQLYIQNPHITDEPDW-MYTTEASTTVDEYGTVTPAVPRL 307

  Fly   331 --ADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQE 393
              .|...::|  .|...|.:
Mosquito   308 PDLDSEPHYP--EPDPLPTS--------------------------------------------- 325

  Fly   394 EERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRR 458
                                        .|:.                      ....|..|...
Mosquito   326 ----------------------------TPAL----------------------SSTTEVYDIPI 340

  Fly   459 ERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAI 523
            ....|.:...:..:|:.|:.| .||:.||| |.::|...:        ....|.||.|...:|||
Mosquito   341 TFVGDYETVDDHISRHHAQSP-PPTSVTTP-PDDRPPAAI--------PSYVPVPDICSGSFDAI 395

  Fly   524 SIIRGELFIFRGPYLWRIGTS-GLYNGYPTEIRRHWSALPENLTKVDAVYEN-KQRQIVFFIGRE 586
            .::|||:|||:|.||||:... .:..|||..|.:.:...|:.::.:|||||. ....||.|.||.
Mosquito   396 GLLRGEIFIFKGAYLWRLTEKYRIKTGYPVRIWQVFRGFPKTVSHIDAVYERLDDNAIVLFSGRF 460

  Fly   587 YYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPR 651
            |:||:::.......:||...|||..|..|||:.||..||:||:.:|..:||.:|..|:::..||.
Mosquito   461 YWVFDALNFLHPEVRPLTDFGLPEELRRIDAALVWPKNNKTYLFAGDRFWRYNDTAGEMDEGYPS 525

  Fly   652 DMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQC 707
            .|..|.|:..|||||.....|||||||...||.:|::|::......:.:...|:.|
Mosquito   526 SMDRWFGIPNNIDAATAVASGKTYFFKGNYYWLYNNERVRPERGYPRRTGNIWLGC 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	15/50 (30%)
		Peptidase_M10	143..301	CDD:425668	75/168 (45%)
		HX	513..707	CDD:238046	77/195 (39%)
LOC3290935	XP_061502994.1	None