Protein Alignment Mmp2 and Mmp19

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001100629.1
• Gene: Mmp19 / 304608
• RGDID: 1311376
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 170/679 - (25%)
• Similarity: 253/679 - (37%)
• Gaps: 227/679 - (33%)

  Fly    36 TRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGA--LRTEDQLKEAIRSLQSFGNITVTGEIDSA 98
            |.|.:|.....::.:.:||:|:.||.| .|| ||  .|.|| :.||:|:.|....:.|:|::|.|
  Rat    15 TVSGRALGPAEKEAVVDYLLQYGYLQK-PLE-GADDFRLED-ITEALRTFQEASELPVSGQMDDA 76

  Fly    99 TARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVN-RSMPDAS 162
            |...:::||||:     .|.|           |.:..::.|.| .|.:..||:.::| .|....|
  Rat    77 TRARMKQPRCGL-----EDPF-----------NQKTLKYLLLG-HWRKKHLTFRILNVPSTLSPS 124

  Fly   163 KVERMVQTALDVWANHSKLTFREVYSDQADIQILF-ARRAHGDGYKFDGPGQVLAHAFYPGEGRG 226
            :|...:..|...|:|.:.||||||.:..|||::.| .|::......|||||:|||||..|   ..
  Rat   125 RVRAALHQAFKYWSNVAPLTFREVKAGWADIRLSFHGRQSPYCSNSFDGPGKVLAHADVP---EL 186

  Fly   227 GDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDD 291
            |..|||.||.|.    .....|.|...:|.||:||:|||.||....|:|.|.|...:....|..|
  Rat   187 GSVHFDNDEFWT----EGTYQGVNLRIIAAHEVGHALGLGHSRYTQALMAPVYAGYQPYFRLHPD 247

  Fly   292 DRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARER 356
            |..|||.|||
  Rat   248 DVAGIQALYG------------------------------------------------------- 257

  Fly   357 QEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWER 421
                                                                             
  Rat   258 ----------------------------------------------------------------- 257

  Fly   422 NPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANT 486
                            :||.|.|.:|:|.:                                .:|
  Rat   258 ----------------KRRPEPEDEEEEVE--------------------------------MHT 274

  Fly   487 TPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISI-IRGELFIFRGPYLWRIGTSGLYNGY 550
            ....|.||               .|.|:.|.:..||:.: .||:.:.|:|.|:|.:..||  .|.
  Rat   275 VSTVTTKP---------------SPMPNPCSSEVDAMMLGPRGKTYAFKGDYVWTVTDSG--PGP 322

  Fly   551 PTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHI 615
            ...:...|..||.||..  |||..:.::..||.|.:.:.:....|:||||..|..  :.|.|
  Rat   323 LFRVSALWEGLPGNLDA--AVYSPRTQRTHFFKGNKVWRYVDFKLSPGFPMKLNR--VEPNL--- 380

  Fly   616 DASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDM-SIWSGVGYNIDAAFQYLDGKTYFFKN 679
            ||:..|..|.:.::..|:.||:.|:.|......||:.: .:::||.....||..:.||:.||||.
  Rat   381 DAALYWPVNQKVFLFKGSGYWQWDELTRTDLSRYPKPIKELFTGVPDQPSAAMSWQDGQVYFFKG 445

  Fly   680 LGYWEFNDDRMKVAHARAKLSARRWMQCA 708
            ..||..| .:::||....: :...||.|:
  Rat   446 KEYWRLN-QQLRVAKGYPR-NTTHWMHCS 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	62/159 (39%)
		ZnMc_MMP	143..301	CDD:239805	62/159 (39%)
		HX	513..707	CDD:238046	60/195 (31%)
Mmp19	NP_001100629.1	PG_binding_1	27..81	CDD:396175	22/56 (39%)
		ZnMc_MMP	105..257	CDD:239805	62/158 (39%)
		HX	286..471	CDD:238046	60/195 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920