Protein Alignment Mmp2 and Mmp28

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001073357.1
• Gene: Mmp28 / 303384
• RGDID: 1311573
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 691
• Identity: 157/691 - (22%)
• Similarity: 245/691 - (35%)
• Gaps: 237/691 - (34%)

  Fly    53 YLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSAD 117
            :|.::.||.:...:..|   ..|..:|||..|....:.::|.:|.||.|.:.:|||||.|..|.:
  Rat    39 FLEKYGYLSEQGSKVPA---STQFSDAIREFQWVSQLPISGVLDRATLRQMTRPRCGVADTDSHE 100

  Fly   118 SFSPDNLYHEIGSNVRVR---RFALQGPKWSRTDLTWSMVN--RSMPDASKVERMVQTALDVWAN 177
            :::........|...::|   |||..|.||.:..|::.:||  :|:|:.: |...|:.|..:|:|
  Rat   101 TWTERIRALLAGHRAKMRRKKRFAKPGHKWYKQHLSYRLVNWPKSLPEPA-VRGAVRAAFQLWSN 164

  Fly   178 HSKLTFREV-YSDQADIQILFARRAHGDGY--KFDGPGQVLAHAFYPGEGRGGDAHFDADETWNF 239
            .|.|.|.|. .:..|||::.|.:..|.||.  .|||||..|||||.|   |.|:||||.||.|:.
  Rat   165 VSALEFWEAPATGPADIRLTFFQGDHNDGLANAFDGPGGALAHAFLP---RRGEAHFDQDERWSL 226

  Fly   240 DGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKE 304
            ...    .|.|...|..||:||:|||.||..|.|:|.|:|:.......|..||...:|.|||
  Rat   227 SRR----RGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKKLGRDALLSWDDVLAVQNLYG--- 284

  Fly   305 KTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERR 369
                  ||...:..|
  Rat   285 ------KPLGRSVAT-------------------------------------------------- 293

  Fly   370 RQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQ 434
                           |:..:...:.|.|
  Rat   294 ---------------QLPGKIFTDFEAW------------------------------------- 306

  Fly   435 EMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVH 499
                                                       :|
  Rat   307 -------------------------------------------DP-------------------- 308

  Fly   500 RQHHHHNKPRKPK---PDSCMTYYDAISII-RGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSA 560
                |:::.|:|:   |..|.:.:|||::. :..|::|:|.:.|.:...|..: .|..:::.|..
  Rat   309 ----HNSQSRRPETRGPKYCHSSFDAITVDGQWRLYVFKGSHFWEVTADGNVS-EPHPLQKRWPG 368

  Fly   561 LPENLTKVDAVYENKQRQIVFFIGREYY-------VFNSVMLAPGFPK-PLASLGLPPTLTHIDA 617
            ||.::..  |....:.....||.|...:       ||..:..|.|.|: |.|:|..||.
  Rat   369 LPSSIEA--AAVSLEDGDFFFFKGNRCWRFQGTKSVFAQLCRAGGLPRHPDAALFFPPL------ 425

  Fly   618 SFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMSIWSGVGYNIDAAFQYLDGKTYFFKNLGY 682
                   .|..:..|:.|:.:.....|||..|||.:..|:||...:..|....||...||::..|
  Rat   426 -------RRLVLFKGSRYYVLARGGMQVEPYYPRSLRDWAGVPEEVSGALPRPDGSIIFFRDDHY 483

  Fly   683 WEFNDDRMKVAHARAKLSARRWMQCARSANEVDDEQRWTAS 723
            |..:..:::|..:....:...||.|            |.|:
  Rat   484 WHLDQAKLRVTSSGRWATELSWMGC------------WNAN 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	14/49 (29%)
		Peptidase_M10	143..301	CDD:425668	65/162 (40%)
		HX	513..707	CDD:238046	50/202 (25%)
Mmp28	NP_001073357.1	PG_binding_1	34..86	CDD:460223	14/49 (29%)
		ZnMc_MMP	129..284	CDD:239805	65/162 (40%)
		HX	321..508	CDD:238046	50/202 (25%)