Protein Alignment Mmp2 and Mmp1

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001128002.1
• Gene: Mmp1 / 300339
• RGDID: 1307917
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 725
• Identity: 171/725 - (23%)
• Similarity: 245/725 - (33%)
• Gaps: 288/725 - (39%)

  Fly     7 LATLLALFAQSMCIQELSLP--PEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGA 69
            |..||.|.|.|    ..|.|  .:|:.....|             ::.||..: |....|::...
  Rat     4 LPLLLLLLATS----SYSFPVFQDGARQNVET-------------VWKYLENY-YNLGEDVQAKN 50

  Fly    70 LRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRV 134
            :..::.:.|.:|.:|....:.|||..:|.|...::||||||.|      .:|..:.|
  Rat    51 VDAKEVMAEKLRQMQQLFGLKVTGNSNSETLSAMRKPRCGVPD------VAPYAITH-------- 101

  Fly   135 RRFALQGPKWSRTDLTWSMVNRSMPDASK--VERMVQTALDVWANHSKLTFREVYSDQADIQILF 197
                 ..|:|::|.||:|::|.: |...|  :|..::.|..||::.:.|||..|:.::.||...|
  Rat   102 -----NNPRWTKTHLTYSILNYT-PYLPKEVIENAIERAFKVWSDVTPLTFERVFEEEGDIVFAF 160

  Fly   198 ARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHS 262
            .|..|.|...||||...|||.|.||...|||.|:|.||||     :|:|...|...|..||||||
  Rat   161 YRGDHSDNNPFDGPEYGLAHTFPPGPRLGGDVHYDLDETW-----TDNSDNFNLFYVTAHELGHS 220

  Fly   263 LGLAHSAIPDAVMFP---WYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTM 324
            |||.||....|:|||   ||..:.|   |..:|...||.|||
  Rat   221 LGLTHSRDVGALMFPSYTWYTEDFV---LNQEDINRIQALYG----------------------- 259

  Fly   325 RAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEER 389
                             ||.|
  Rat   260 -----------------PSPN-------------------------------------------- 263

  Fly   390 QRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQE 454
                                                                             
  Rat   264 ----------------------------------------------------------------- 263

  Fly   455 DRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTY 519
                                    |:.||..|||.|.                      |..:|
  Rat   264 ------------------------PIQPTGATTPHPC----------------------DGDLT- 281

  Fly   520 YDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRH-----WSALPENLTKVDAVYE-NKQRQ 578
            :|||:..|||:..|:|.:..|:      |.:..|...:     |..||   .|:||.|| :...|
  Rat   282 FDAITTFRGEVMFFKGRFYIRV------NKFMPEAELNLIGIIWPNLP---GKLDAAYEVSMIDQ 337

  Fly   579 IVFFIGREYYVFNSVMLAPGFPKPLAS-LGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYT 642
            :.:|.|.:.:|.....:..|||..:.| .|.|.::|||||:.......:||.....:|||.|:.|
  Rat   338 VRYFKGNKVWVVREHTVLRGFPTDIHSFFGFPSSVTHIDAAVCEEETGKTYFFVDNMYWRYDENT 402

  Fly   643 GQVELDYPR-DMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARR--- 703
            ..::..||| ....:.|:...:|..||  .|:.::|       |:..    ...|..|..||
  Rat   403 QSMDPGYPRLTAEDFPGIDDKVDDVFQ--KGENFYF-------FHQS----VQRRFSLRIRRVDD 454

  Fly   704 ------WMQC 707
                  |..|
  Rat   455 SRDSSTWFNC 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	68/162 (42%)
		ZnMc_MMP	143..301	CDD:239805	68/162 (42%)
		HX	513..707	CDD:238046	58/210 (28%)
Mmp1	NP_001128002.1	PG_binding_1	26..84	CDD:279773	13/71 (18%)
		Peptidase_M10	105..259	CDD:278824	68/162 (42%)
		ZnMc_MMP	105..259	CDD:239805	68/162 (42%)
		HX	273..464	CDD:238046	60/235 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4331
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820