Protein Alignment Mmp2 and Mmp21

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001099778.1
• Gene: Mmp21 / 293573
• RGDID: 1309332
• Length: 568
• Species: Rattus norvegicus
• Alignment Length: 727
• Identity: 150/727 - (20%)
• Similarity: 230/727 - (31%)
• Gaps: 292/727 - (40%)

  Fly    40 KAKTAISEDIMYNYLMQFDYLP-KSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLI 103
            :||.........|:|:::.:.. .|..|:..:.....|.:|:|..|....:..:|::||.|...:
  Rat    43 RAKPIADLHAAQNFLLKYGWSEVSSPKESAGVPVGFTLAQAVRRFQKANRLPASGKLDSPTLAAM 107

  Fly   104 QKPRCGVGDRR--SADSF-SPDNLYHEIGSNVRVR--RFALQ-------GPKWSRTD-------- 148
            .||||||.|.|  ..|:. :|..|...:|...|.|  || ||       |.:..|:|
  Rat   108 NKPRCGVPDTRLPLQDALPTPPALPTPLGLQPRARQKRF-LQMLLPKPGGKQEGRSDTGASRVFS 171

  Fly   149 ---LTWSMVN---RSMPDASKVERMVQTALDVWANHSKLTFRE---VYSDQADIQILFARRAH-G 203
               |||.:|.   .|.....:...:.:.|..:|:..:.|.|||   ......||::.|.|..| |
  Rat   172 KKTLTWRLVGDAYSSQLSGDEQRYIFRLAFRMWSEVTPLDFREDLTAPGTMVDIKLGFGRGRHLG 236

  Fly   204 DGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHS 268
            ....|||.||..|||::.||     .|||.||  :|...|.|: |.:.|.||:||:||.|||.|:
  Rat   237 CPRVFDGSGQEFAHAWHLGE-----IHFDDDE--HFTPLSSDT-GISLLKVAVHEIGHVLGLPHT 293

  Fly   269 AIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADK 333
            ....::|.|.|...|.|..|...||..||:|||:.|.::
  Rat   294 YRVGSIMQPNYIPQEPAFELDWSDRKAIQRLYGSCEGSF-------------------------- 332

  Fly   334 PAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWR 398
                                                                             
  Rat   333 ----------------------------------------------------------------- 332

  Fly   399 QEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERD 463
                                                                            |
  Rat   333 ----------------------------------------------------------------D 333

  Fly   464 RQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRG 528
            ...:|.|:.||                   .|..|.                          :|.
  Rat   334 IVFDWIRKERN-------------------QYGEVR--------------------------VRF 353

  Fly   529 ELFIFRGPYLWRIGTSGLYN--------GYPTEIRRHWSALPENLTKVDA---VYENKQRQIVFF 582
            ..:.||..:.|      ||.        |.|.:|...|..:|  :.::||   |:...:.:..||
  Rat   354 NTYFFRNSWYW------LYENRNNRTRYGDPLQILTGWRGIP--MQRIDAFVHVWSWGRDERYFF 410

  Fly   583 IGREYYVFNS----------------VMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTS 631
            .|.:|:.::|                .:::.|||      |:|..|   |.:|........|...
  Rat   411 KGNQYWRYDSENDQAHTQDEQGRSYPKLISEGFP------GIPSPL---DTAFYERRQQLIYFFK 466

  Fly   632 GTLYWRIDDYTGQVELDYPRDMS-IWSGV------GYNIDAA-FQYLDGKTYFFKNLGYWEFNDD 688
            .:|.:..|....|....||:.|| ::..:      ..|:|:| :.|.....:|||...:|:...|
  Rat   467 ESLVYAFDVNRNQALSSYPKKMSQVFPAIMPQNHPFRNLDSAYYSYAHNAIFFFKGNSFWKVVSD 531

  Fly   689 RMKVAHARAKLS 700
            :.|...:|..|:
  Rat   532 KDKQQDSRLPLN 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	60/175 (34%)
		ZnMc_MMP	143..301	CDD:239805	60/175 (34%)
		HX	513..707	CDD:238046	47/223 (21%)
Mmp21	NP_001099778.1	PG_binding_1	48..107	CDD:279773	12/58 (21%)
		Peptidase_M10	170..326	CDD:278824	58/163 (36%)
		ZnMc_MMP	170..326	CDD:239805	58/163 (36%)
		HX	355..544	CDD:238046	46/206 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920