Protein Alignment Mmp2 and Vtn

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_035837.1
• Gene: Vtn / 22370
• MGIID: 98940
• Length: 478
• Species: Mus musculus
• Alignment Length: 255
• Identity: 63/255 - (24%)
• Similarity: 97/255 - (38%)
• Gaps: 89/255 - (34%)

  Fly   466 LEWERRNRNGAREP--------VTPTANTTPRPT---------NKPYPTVHRQHH-------HHN 506
            :|..:.|.|...:|        :.|..:.|.:||         :.|.|.|.:|..       ...
Mouse    81 VEEPKNNTNTGVQPENTSPPGDLNPRTDGTLKPTAFLDPEEQPSTPAPKVEQQEEILRPDTTDQG 145

  Fly   507 KPRKPKPDSCM-TYYDAISIIR-GELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVD 569
            .|..|:.:.|. ..:||.:.:: |.||.|||.|.:.:..:.:..|||..|:..|
Mouse   146 TPEFPEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVW----------- 199

  Fly   570 AVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFV-WGHNNRTYMTSGT 633
                                        |...|            |||:|. .....:||:..|:
Mouse   200 ----------------------------GIEGP------------IDAAFTRINCQGKTYLFKGS 224

  Fly   634 LYWRIDDYTGQVELDYPRDMSI-WSGVGYNIDAAF-----QYLDG--KTYFFKNLGYWEF 685
            .|||.:|  |.::..|||::|. :||:..|:||||     :| .|  :.||||...|||:
Mouse   225 QYWRFED--GVLDPGYPRNISEGFSGIPDNVDAAFALPAHRY-SGRERVYFFKGKQYWEY 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223
		Peptidase_M10	143..301	CDD:425668
		HX	513..707	CDD:238046	49/184 (27%)
Vtn	NP_035837.1	Somatomedin_B	22..61	CDD:460034
		Cell attachment site	64..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..153		14/70 (20%)
		HX	153..473	CDD:238046	49/183 (27%)
		Hemopexin 1	157..201		14/82 (17%)
		Hemopexin 2	202..249		18/60 (30%)
		Hemopexin 3	250..304		14/33 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	359..395
		Heparin-binding. /evidence=ECO:0000250	366..399
		Hemopexin 4	420..473