DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mmp2 and Vtn

DIOPT Version :9

Sequence 1:NP_995788.1 Gene:Mmp2 / 35997 FlyBaseID:FBgn0033438 Length:758 Species:Drosophila melanogaster
Sequence 2:NP_035837.1 Gene:Vtn / 22370 MGIID:98940 Length:478 Species:Mus musculus


Alignment Length:255 Identity:63/255 - (24%)
Similarity:97/255 - (38%) Gaps:89/255 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   466 LEWERRNRNGAREP--------VTPTANTTPRPT---------NKPYPTVHRQHH-------HHN 506
            :|..:.|.|...:|        :.|..:.|.:||         :.|.|.|.:|..       ...
Mouse    81 VEEPKNNTNTGVQPENTSPPGDLNPRTDGTLKPTAFLDPEEQPSTPAPKVEQQEEILRPDTTDQG 145

  Fly   507 KPRKPKPDSCM-TYYDAISIIR-GELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVD 569
            .|..|:.:.|. ..:||.:.:: |.||.|||.|.:.:..:.:..|||..|:..|           
Mouse   146 TPEFPEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVW----------- 199

  Fly   570 AVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFV-WGHNNRTYMTSGT 633
                                        |...|            |||:|. .....:||:..|:
Mouse   200 ----------------------------GIEGP------------IDAAFTRINCQGKTYLFKGS 224

  Fly   634 LYWRIDDYTGQVELDYPRDMSI-WSGVGYNIDAAF-----QYLDG--KTYFFKNLGYWEF 685
            .|||.:|  |.::..|||::|. :||:..|:||||     :| .|  :.||||...|||:
Mouse   225 QYWRFED--GVLDPGYPRNISEGFSGIPDNVDAAFALPAHRY-SGRERVYFFKGKQYWEY 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mmp2NP_995788.1 Peptidase_M10 143..301 CDD:278824
ZnMc_MMP 143..301 CDD:239805
HX 513..707 CDD:238046 49/184 (27%)
VtnNP_035837.1 SO 20..62 CDD:197571
Cell attachment site 64..66
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 82..153 14/70 (20%)
HX 153..473 CDD:238046 49/183 (27%)
Hemopexin 1 157..201 14/82 (17%)
Hemopexin 2 202..249 18/60 (30%)
Hemopexin 3 250..304 14/33 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 359..395
Heparin-binding. /evidence=ECO:0000250 366..399
Hemopexin 4 420..473
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1565
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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