DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mmp2 and K03B8.6

DIOPT Version :10

Sequence 1:NP_995788.1 Gene:Mmp2 / 35997 FlyBaseID:FBgn0033438 Length:758 Species:Drosophila melanogaster
Sequence 2:NP_505894.2 Gene:K03B8.6 / 186927 WormBaseID:WBGene00010524 Length:331 Species:Caenorhabditis elegans


Alignment Length:284 Identity:67/284 - (23%)
Similarity:104/284 - (36%) Gaps:84/284 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   418 QWERNPSKERNRPRERQEMERRRQEQERQEQERQEQED---RRRERERDRQ----LEWERRNRNG 475
            |:|.|..:....|        |...|.:.|..|...:|   |||:.::.||    |..|||:...
 Worm    51 QYEVNSEEVPTLP--------RMNSQTKWEMIRASGQDPTVRRRKNKQHRQQKVVLGRERRDLIL 107

  Fly   476 AREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRK-----PKP------DSCMTYYDAISI-IRG 528
            |...:|                       |..|:|     ||.      |.|...:|||:. |.|
 Worm   108 APWRIT-----------------------HVVPKKKEAEVPKKAMALSFDVCPEKFDAITKGING 149

  Fly   529 ELFIFRGPYLWRIGTSGLYNGYPTE----IRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYV 589
            ..::|....:::|   ...:|.|.:    |...::..|..:|.  |:..::....:.|.||..|.
 Worm   150 RTYVFARERVYQI---WFEDGLPQKASYLISEFFAGGPRTVTA--ALTNSRSGVTILFDGRTAYR 209

  Fly   590 F------NSVMLAPGFPKPLASLGLPPTLT-HIDASFVWGHNNRTYMTSG------TLYWRIDDY 641
            |      ....||...|:     .||..:| |..::|.|...|:..: ||      ..||.:..:
 Worm   210 FRWNRKHRRFQLAKNTPQ-----DLPRNITIHPLSAFEWADGNQVVL-SGEHFIIYDAYWNLATF 268

  Fly   642 TGQVEL---DYPRDMSIWSGVGYN 662
            ||....   :.|||:   .|:.||
 Worm   269 TGHTRKYFPNLPRDL---LGIVYN 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mmp2NP_995788.1 PG_binding_1 52..103 CDD:460223
Peptidase_M10 143..301 CDD:425668
HX 513..707 CDD:238046 42/177 (24%)
K03B8.6NP_505894.2 HX 134..>265 CDD:413329 34/141 (24%)
Blue background indicates that the domain is not in the aligned region.

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