Protein Alignment Mmp2 and zmp-1

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_741156.1
• Gene: zmp-1 / 175839
• WormBaseID: WBGene00006987
• Length: 521
• Species: Caenorhabditis elegans
• Alignment Length: 665
• Identity: 132/665 - (19%)
• Similarity: 223/665 - (33%)
• Gaps: 262/665 - (39%)

  Fly    53 YLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSAD 117
            :|.::.||...|.:.    :.:.|.:|::::|....:..|||:|..|.:::::||||
 Worm    29 FLQKYGYLTSGDNQL----SSESLSDALKNMQRMAGLEETGELDERTIQMMERPRCG-------- 81

  Fly   118 SFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTW------SMVNRSMPDASKVERMVQTALDVWA 176
              .||...|:   ..|.:|:|....||....:|:      :....|:.|   :.|.:..|...|
 Worm    82 --HPDVEDHQ---KSRGKRYAPPQFKWKEKIITYGCKAVGTSTRISLDD---LRRTMHQAASQW- 137

  Fly   177 NHSKLTFREVYSDQADIQIL------------FARRAHGDGY----KFDGPGQVLAHAFYPGEGR 225
                       |:.||::|:            ..|..|   |    :||  .:.|||||:|   .
 Worm   138 -----------SELADVEIVESSVKNPMMVISAGRENH---YPCTVRFD--TKTLAHAFFP---T 183

  Fly   226 GGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPD 290
            .|..|.:....:.....::.....:..:|..||:||:||.:||...|:|||.:  :.........
 Worm   184 NGQIHINDRVQFAMTNYTERMGANSLYSVVAHEMGHALGFSHSPDIDSVMFAY--DTPRKWKFTS 246

  Fly   291 DDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARE 355
            .|:|.::..||.|                           |.|                    :|
 Worm   247 MDKYNMRSYYGAK---------------------------ASK--------------------KE 264

  Fly   356 RQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWE 420
            .:||||                                         :.|.|::|||.|
 Worm   265 NEEEER-----------------------------------------KTENEDKRRKTE------ 282

  Fly   421 RNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTAN 485
                |:|.|.||                  .|.:|.|
 Worm   283 ----KDRGRTRE------------------HESDDIR---------------------------- 297

  Fly   486 TTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSG---LY 547
                                       |:.|......:...|||..||:..::||:.:..   :.
 Worm   298 ---------------------------PNECRVENPIVVQYRGEYLIFKSQWVWRVSSDWKRLII 335

  Fly   548 NGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVF--NSVMLAPGFPKPLASLGLPP 610
            ...|  |.:.:..||..:.....|..|    :..|:|...||.  |.::.|   |..|:.:|:
 Worm   336 KAVP--INQLFPGLPNPIDAAVTVGHN----LWVFVGEMIYVIYGNHMVHA---PLRLSDIGI-- 389

  Fly   611 TLTHIDASFVWGHNN--RTYMTSGTLYWRIDD--YTGQVELDYPRDMSI-WSGVGYNIDAAFQY- 669
            ...::|.::.|.:.|  ..|:..|:.||::|:  |..:|:..||:|..: |:.|...:.:||.|
 Worm   390 NEKYVDLAYEWHYFNPPAVYIWKGSRYWKLDEKMYHRRVDERYPKDTDLNWARVPKGVHSAFTYE 454

  Fly   670 -----LDGKTYFFKN 679
                 |.|...|..|
 Worm   455 KEIHLLRGNQVFRMN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	40/179 (22%)
		ZnMc_MMP	143..301	CDD:239805	40/179 (22%)
		HX	513..707	CDD:238046	46/183 (25%)
zmp-1	NP_741156.1	PG_binding_1	28..75	CDD:307564	12/49 (24%)
		ZnMc_MMP	102..257	CDD:239805	40/179 (22%)
		HX	308..483	CDD:238046	44/173 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22669
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810