Protein Alignment Mmp2 and Mmp2

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_006530814.1
• Gene: Mmp2 / 17390
• MGIID: 97009
• Length: 704
• Species: Mus musculus
• Alignment Length: 787
• Identity: 181/787 - (22%)
• Similarity: 276/787 - (35%)
• Gaps: 255/787 - (32%)

  Fly    47 EDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVG 111
            :::...||..|...||.......      ||:.::.:|.|..:..||::|..|...::|||||
Mouse    47 KELAVQYLNTFYGCPKESCNLFV------LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCG-- 103

  Fly   112 DRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRSMP-DASKVERMVQTALDVW 175
                    :||         |....|..:.|||.:..:|:.::..:.. |...|:.....||.||
Mouse   104 --------NPD---------VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVW 151

  Fly   176 ANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETW--- 237
            ::.:.|.|..::..:|||.|.|.|..|||||.|||...:|||||.||.|.|||:|||.||.|
Mouse   152 SDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLG 216

  Fly   238 ----------NFDGESDD----SHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNL 288
                      |.|||...    .:|..:.:..  :.|.|.|           |.|.....   |.
Mouse   217 EGQVVRVKYGNADGEYCKFPFLFNGREYSSCT--DTGRSDG-----------FLWCSTTY---NF 265

  Fly   289 PDDDRYGIQQLYGTKEKTWGPYKPQTTTTT-------------------------------TTTT 322
            ..|.:||           :.|::..|...|                               ..|.
Mouse   266 EKDGKYG-----------FCPHEDPTHGLTHGRADLLHHRLLSSALFMLLSRKLNFVVRLKLLTI 319

  Fly   323 TMRAMIYRAD-KPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQV 386
            |:..|...|| :|..:|:.....:.|:.....
Mouse   320 TLFTMGGNADGQPCKFPFRFQGTSYNSCTTEG--------------------------------- 351

  Fly   387 EERQRQEEERWRQEQERQEEENR----------------------------RRKIEHKSQWERNP 423
                |.:..||....|..:.:.:                            ..|.|..:...||.
Mouse   352 ----RTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRND 412

  Fly   424 SKERNRPRERQEMERRRQEQERQEQERQEQEDRR------------------------RERERD- 463
            .|.........:                  :||:                        .|..:|
Mouse   413 GKVWCATTTNYD------------------DDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDP 459

  Fly   464 -----------RQLEWERRNRNGAREPVTPT------ANTTPRPTNKPYPTVHRQHHHHNKPRKP 511
                       :.......:..|.:|...|:      ..|.|.||..|.
Mouse   460 GALMAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPV---------------- 508

  Fly   512 KPDSCM--TYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYEN 574
            .|:.|.  ..:|.|:.||||:|.|:..::||..|.......|..:...|..|||   |:|||||.
Mouse   509 TPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPE---KIDAVYEA 570

  Fly   575 KQRQ-IVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRI 638
            .|.: .|||.|.||:|:::..|..|:||||.||||||.:..:||:|.|..|.:||:.:|..:||.
Mouse   571 PQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRY 635

  Fly   639 DDYTGQVELDYPRDMS-IWSGVGYNIDAAFQYL-DGKTYFFKNLGYWEFNDDRMK-VAHARAKLS 700
            ::...:::..:|:.:: .|:.:..|:||..... .|.:||||...|.:..:..:| |.....|..
Mouse   636 NEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSD 700

  Fly   701 ARRWMQC 707
               |:.|
Mouse   701 ---WLGC 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	56/175 (32%)
		ZnMc_MMP	143..301	CDD:239805	56/175 (32%)
		HX	513..707	CDD:238046	69/199 (35%)
Mmp2	XP_006530814.1	PG_binding_1	<70..97	CDD:366659	6/26 (23%)
		Peptidase_M10	118..>219	CDD:334067	33/101 (33%)
		FN2	226..274	CDD:128373	17/64 (27%)
		FN2	326..374	CDD:128373	6/48 (13%)
		FN2	384..432	CDD:128373	9/75 (12%)
		ZnMc	<408..489	CDD:214576	13/150 (9%)
		HX	510..704	CDD:238046	68/199 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920