Protein Alignment Mmp2 and Mmp2

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_061509542.1
• Gene: Mmp2 / 1280787
• VectorBaseID: AGAMI1_014658
• Length: 718
• Species: Anopheles gambiae
• Alignment Length: 720
• Identity: 300/720 - (41%)
• Similarity: 403/720 - (55%)
• Gaps: 113/720 - (15%)

  Fly    37 RSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATAR 101
            |..:||....:|.:..|||||.||.||::|||.|||.::|::|:||||.||.:..||.:|..|..
Mosquito    61 RRSEAKFWDYDDSVQKYLMQFGYLEKSNIETGNLRTIEELEQAVRSLQRFGGLKETGTVDEETLA 125

  Fly   102 LIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRSMP--DASKV 164
            |:|:||||..|.:.:..|.|.  |.......|.||:.:||.||....:|:|:||::|.  ||.:|
Mosquito   126 LMQRPRCGAPDDKDSLDFRPS--YEVRLKRSRSRRYVIQGQKWQNPIVTYSLVNQTMSELDAGQV 188

  Fly   165 ERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDA 229
            .|::..||.:||.|:.:.||||||..||||::|||:.|||||.|||||::||||||||.|.||||
Mosquito   189 RRILHEALGLWAQHANINFREVYSTDADIQVMFARKFHGDGYNFDGPGKILAHAFYPGTGIGGDA 253

  Fly   230 HFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPW----YQNNEVAGNLPD 290
            ||||||.|..: |..|:.||...:||:||.||||||.||:..||:||||    |:..:   .:|:
Mosquito   254 HFDADEKWLLN-EPLDAEGTRLFDVAVHEFGHSLGLGHSSQQDAIMFPWHHISYRGKD---TIPE 314

  Fly   291 DDRYGIQQLYGTKEKTWG--PYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNP-----NN 348
            |||.|||.:||.::|.:|  |.:...:||||||||..|...|.....|:|..|.:.:|     .:
Mosquito   315 DDRLGIQSIYGPRKKIYGKNPERHTPSTTTTTTTTTPAPPPRPTTRPYYPVKNTTGHPWEGLYPH 379

  Fly   349 DRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKI 413
            .|.....|........|:...|.:||.|:                                  :.
Mosquito   380 GRPYTTRRTTTTTTTTERSHHRGDEETRY----------------------------------RT 410

  Fly   414 EHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGARE 478
            :|.:..|  .:..|:||..|.                                    .:|.....
Mosquito   411 QHPATTE--TTTVRHRPHHRP------------------------------------HHRTTTTT 437

  Fly   479 PVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGT 543
            .:|.|..||   |.:||.  ||...|        |:.|.|.:|||::||.|||||:..:|||:..
Mosquito   438 AMTTTTTTT---TRRPYR--HRTTIH--------PNPCNTSFDAITLIRNELFIFKDRWLWRMNE 489

  Fly   544 SGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGL 608
            :.|:...|.||.|.:..||.:..::|.|||||.::|:||||::||||||..|.||:|:||..|||
Mosquito   490 NDLHRPTPFEIHRMFFGLPADFERIDTVYENKHQKIIFFIGKQYYVFNSQYLEPGYPRPLTDLGL 554

  Fly   609 PPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMSIWSGVGYNIDAAFQYLDGK 673
            |.::..|||:.||.||||||:.||.|||:.|:.|.:||||||||||:|.|:|||||:||||.|||
Mosquito   555 PDSIERIDAALVWSHNNRTYLYSGRLYWKFDEDTNRVELDYPRDMSMWRGIGYNIDSAFQYRDGK 619

  Fly   674 TYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARS--ANEVDDEQRWTASLV-------SEGE 729
            |||||..|||.|||..|.:||...|.||||||:|...  .|::|::.....::|       |.|.
Mosquito   620 TYFFKGRGYWRFNDMNMSIAHEYQKSSARRWMKCHERLLLNDLDEDIDVPPTVVHTAGVGTSRGT 684

  Fly   730 ETGRS 734
            ..|||
Mosquito   685 SLGRS 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	27/50 (54%)
		Peptidase_M10	143..301	CDD:425668	89/163 (55%)
		HX	513..707	CDD:238046	113/193 (59%)
Mmp2	XP_061509542.1	None